Halloween is een feest dat in Nederland steeds populairder lijkt te worden. Deze tijd van het jaar komen er altijd veel horrorfilms uit waar we ons graag bang door laten maken. Maar is dat niet een beetje gek? Bang zijn is toch helemaal niet leuk? Wat vertelt de wetenschap ons over deze paradox? Afbeelding door […]... Read more »
Linda de Voogd. (2014) Horror paradox. Donders Wonders. info:other/
In Milgram's shock experiments, a surprising number of people obeyed a scientist's instruction to deliver dangerous electric shocks to another person. This is usually interpreted in terms of the power of "strong situations". The scenario, complete with lab apparatus and scientist in grey coat, was so compelling that many people's usual behavioural tendencies were overcome.But a new study challenges this account. Recognising that many participants in fact showed disobedience to the scientist in M........ Read more »
Bègue, L., Beauvois, J., Courbet, D., Oberlé, D., Lepage, J., & Duke, A. (2014) Personality Predicts Obedience in a Milgram Paradigm. Journal of Personality. DOI: 10.1111/jopy.12104
I wanted to switch gears a bit and do a paper on Electron Paramagnetic Resonance (EPR), also know as Electron Spin Resonance (ESR). The paper for this weeks is
Electron spin resonance (ESR/EPR) of free radicals observed in human red hair: a new, simple empirical method of determination of pheomelanin/eumelanin ratio in hair.
Chikvaidze EN, Partskhaladze TM and Gogoladze TV... Read more »
Chikvaidze, E., Partskhaladze, T., & Gogoladze, T. (2014) Electron spin resonance (ESR/EPR) of free radicals observed in human red hair: a new, simple empirical method of determination of pheomelanin/eumelanin ratio in hair. Magnetic Resonance in Chemistry, 52(7), 377-382. DOI: 10.1002/mrc.4075
Vaccines do NOT cause autism. One more time, vaccines DO NOT cause autism. So what does cause autism, that problem has been plaguing scientists for awhile now. Thankfully two major genetic studies of autism and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes ........ Read more »
Iossifov, I., O’Roak, B., Sanders, S., Ronemus, M., Krumm, N., Levy, D., Stessman, H., Witherspoon, K., Vives, L., Patterson, K.... (2014) The contribution of de novo coding mutations to autism spectrum disorder. Nature. DOI: 10.1038/nature13908
De Rubeis, S., He, X., Goldberg, A., Poultney, C., Samocha, K., Ercument Cicek, A., Kou, Y., Liu, L., Fromer, M., Walker, S.... (2014) Synaptic, transcriptional and chromatin genes disrupted in autism. Nature. DOI: 10.1038/nature13772
October was mostly about conferences and funding. And why is no one studying endosymbiosis in Blastocystis?... Read more »
Fletcher S, Caprarelli G, Merif J, Andresen D, Hal SV, Stark D, & Ellis J. (2014) Epidemiology and geographical distribution of enteric protozoan infections in sydney, australia. Journal of public health research, 3(2), 298. PMID: 25343139
Nagel R, Bielefeldt-Ohmann H, & Traub R. (2014) Clinical pilot study: efficacy of triple antibiotic therapy in Blastocystis positive irritable bowel syndrome patients. Gut pathogens, 34. PMID: 25349629
Nowack EC, & Melkonian M. (2010) Endosymbiotic associations within protists. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 365(1541), 699-712. PMID: 20124339
Prodeus TV, Zelia OP, Khlebnikova TA, & Pikul' DA. (2014) [Extraenteric infection caused by Blastocystis spp. in a female patient with liver abscess]. Meditsinskaia parazitologiia i parazitarnye bolezni, 6-9. PMID: 25296418
If you’ve ever tried to get your kids to share a donut, you understand the importance to dividing things equally (and learning crucial lessons…just buy more donuts next time...I mean, seriously!). Cell division is no different—chromosomes and organelles must all get divided equally. Today’s images are from a paper showing how mitochondria are positioned during cell division in order to allow equal segregation.Many years of research have focused on the equal segregation of chromosomes d........ Read more »
Rohn, J., Patel, J., Neumann, B., Bulkescher, J., Mchedlishvili, N., McMullan, R., Quintero, O., Ellenberg, J., & Baum, B. (2014) Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division. Current Biology. DOI: 10.1016/j.cub.2014.09.045
Parkinson’s disease (PD) is the second most frequent neurodegenerative disease, affecting 1-2% of the population over 55 years of age. The main pathological feature of PD is the progressive death of neurons located in the midbrain that produce the neurotransmitter dopamine. These neurons modulate the activity of a collection of ...
The post Dopamine signaling leads to loss of polycomb repression and aberrant gene activation in experimental parkinsonism appeared first on EpiBeat.
... Read more »
Södersten E, Feyder M, Lerdrup M, Gomes AL, Kryh H, Spigolon G, Caboche J, Fisone G, & Hansen K. (2014) Dopamine signaling leads to loss of polycomb repression and aberrant gene activation in experimental parkinsonism. PLoS genetics, 10(9). PMID: 25254549
Obeso, J., Olanow, C., & Nutt, J. (2000) Levodopa motor complications in Parkinson's disease. Trends in Neurosciences. DOI: 10.1016/S1471-1931(00)00031-8
Feyder M, Bonito-Oliva A, & Fisone G. (2011) L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission. Frontiers in behavioral neuroscience, 71. PMID: 22028687
Feyder M, Södersten E, Santini E, Vialou V, LaPlant Q, Watts EL, Spigolon G, Hansen K, Caboche J, Nestler EJ.... (2014) A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB Expression. Biological psychiatry. PMID: 25193242
Santini E, Valjent E, Usiello A, Carta M, Borgkvist A, Girault JA, Hervé D, Greengard P, & Fisone G. (2007) Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(26), 6995-7005. PMID: 17596448
Di Croce, L., & Helin, K. (2013) Transcriptional regulation by Polycomb group proteins. Nature Structural , 20(10), 1147-1155. DOI: 10.1038/nsmb.2669
Gehani SS, Agrawal-Singh S, Dietrich N, Christophersen NS, Helin K, & Hansen K. (2010) Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation. Molecular cell, 39(6), 886-900. PMID: 20864036
Yeah, I know, it’s not genomics–but it’s the history of life on this planet–right? The Paleobiology Database has been keeping records of this ancient biology for a while now, and they have some really nice tools to explore the fossil records and resources that have become available. It’s also interesting to me to see the […]... Read more »
Varela Sara, González-Hernández Javier, Sgarbi Luciano, Marshall Charles, Uhen Mark, Peters Shanan, & McClennen Michael. (2014) paleobioDB: an R package for downloading, visualizing and processing data from the Paleobiology Database. Ecography. DOI: 10.1111/ecog.01154
The most promising and yet most disappointing aspects of the Internet are the written comments left by the general public. On one hand, comment sections are a great democratization of personal opinion. With public commenting, anyone can make their opinion known until the world on whatever topic interests them. On the other hand, comment sections give voice to absolutely […]The post How to Improve Internet Comments appeared first on NeoAcademic.Related articles from NeoAcademic:Us........ Read more »
Stroud, N., Scacco, J., Muddiman, A., & Curry, A. (2014) Changing Deliberative Norms on News Organizations' Facebook Sites. Journal of Computer-Mediated Communication. DOI: 10.1111/jcc4.12104
1.Blind people can't see in dreams:
Blind people are unable to see even in their dreams but they get a rich combination of different senses in their dreams. They get more feelings of taste, smell, touch, and hear in their dreams as compared to normal people.
2. They have fewer feelings of negative emotions:
Blind from birth people have fewer feelings of negative emotions such as anxiety and depression as compared to normal people.
Blind people see more nightmares (Image courtesy of ........ Read more »
Meaidi, A., Jennum, P., Ptito, M., & Kupers, R. (2014) The sensory construction of dreams and nightmare frequency in congenitally blind and late blind individuals. Sleep Medicine, 15(5), 586-595. DOI: 10.1016/j.sleep.2013.12.008
With Halloween coming up right around the corner, there have been an increase in the attention paid to the spookier aspects of archaeology. We are increasingly able to find evidence of […]... Read more »
Osterholtz, A. (2012) The social role of hobbling and torture: Violence in the prehistoric Southwest. International Journal of Paleopathology, 2(2-3), 148-155. DOI: 10.1016/j.ijpp.2012.09.011
And what does it tell us about the importance of people to their dogs?Photo: hitmanphoto / ShutterstockNew fMRI research by Gregory Berns et al (in press) shows that dog’s brains respond differently to the smell of a familiar human compared to an unfamiliar human and other canines – suggesting that certain people are special to their dogs.The research focussed on a part of the brain called the caudate, which has been much investigated in humans, monkeys and rats. The scientists explain that ........ Read more »
Berns, G., Brooks, A., & Spivak, M. (2014) Scent of the familiar: An fMRI study of canine brain responses to familiar and unfamiliar human and dog odors. Behavioural Processes. DOI: 10.1016/j.beproc.2014.02.011
The protists are a catch-all kingdom, neither characteristics nor cladistics can easily group them, or even tell you what one is. Recent studies have begun to identify histories of the plant-like protist phyla based on their flagella. Rhodophyta are a basal phylum, and yet they have no flagella at all, while genomic studies have identified 495 different proteins in chromista flagella, with some being specific to each of the two dissimilar flagella on the organisms. Such diversity within one grou........ Read more »
Fu G, Nagasato C, Oka S, Cock JM, & Motomura T. (2014) Proteomics Analysis of Heterogeneous Flagella in Brown Algae (Stramenopiles). Protist, 165(5), 662-675. PMID: 25150613
Wei Y, Liu Q, Yu J, Feng Q, Zhao L, Song H, & Wang W. (2014) Antibacterial mode of action of 1,8-dihydroxy-anthraquinone from Porphyra haitanensis against Staphylococcus aureus. Natural product research, 1-4. PMID: 25259418
Maggs CA, Fletcher HL, Fewer D, Loade L, Mineur F, & Johnson MP. (2011) Speciation in red algae: members of the Ceramiales as model organisms. Integrative and comparative biology, 51(3), 492-504. PMID: 21742776
Strauch SM, Richter P, Schuster M, & Häder DP. (2010) The beating pattern of the flagellum of Euglena gracilis under altered gravity during parabolic flights. Journal of plant physiology, 167(1), 41-6. PMID: 19679374
by Rita Handrich in The Jury Room
We’ve written before about the inaccuracy of eye witness testimony despite the familiarity of the saying, “I know what I saw!”. But here is newly published research purporting to have been “able to discriminate perfectly between 12 knowledgeable subjects who viewed stimuli related to their activities and 12 non-knowledgeable subjects who viewed only irrelevant items”. […]
“That witness is lying and I can prove it”
Brain Porn? That is so 2008. Neuro-skepticism........ Read more »
Meixner JB, & Rosenfeld JP. (2014) Detecting Knowledge of Incidentally Acquired, Real-World Memories Using a P300-Based Concealed-Information Test. Psychological Science. PMID: 25231899
"Asperger Syndrome, when considered as an ASD/PDD [autism spectrum disorder/pervasive developmental disorder] diagnosis, was fairly stable into adulthood, but there was a significant increase over time in cases no longer meeting criteria for an ASD diagnosis according to the DSM-IV, or AS according to the Gillberg criteria".The night is darkest just before the dawn.That was one of the primary conclusions made in the paper by Adam Helles and colleagues  who prospectively followed a group ........ Read more »
Adam Helles, Carina I. Gillberg, Christopher Gillberg, & Eva Billstedt. (2014) sperger syndrome in males over two decades: stability and predictors of diagnosis. Journal of Child Psychology and Psychiatry. info:/doi: 10.1111/jcpp.12334
Autograft selection for anterior cruciate ligament (ACL) revision has better outcomes post surgery compared with allografts. ... Read more »
MARS Group, ., Wright, R., Huston, L., Haas, A., Spindler, K., Nwosu, S., Allen, C., Anderson, A., Cooper, D., DeBerardino, T.... (2014) Effect of Graft Choice on the Outcome of Revision Anterior Cruciate Ligament Reconstruction in the Multicenter ACL Revision Study (MARS) Cohort. The American Journal of Sports Medicine, 42(10), 2301-2310. DOI: 10.1177/0363546514549005
Will the amount of online communications affect face-to-face (FtF) relational outcomes among online daters? Researchers analysed experience of using various online date sites of 433 online daters recruited by a market research firm.... Read more »
Ramirez, A., Bryant Sumner, E., Fleuriet, C., & Cole, M. (2014) When Online Dating Partners Meet Offline: The Effect of Modality Switching on Relational Communication Between Online Daters. Journal of Computer-Mediated Communication. DOI: 10.1111/jcc4.12101
You know how some zombie movies start with a discovery of a virus, it gets loose, and things quickly spiral out of control from that? Well in breaking news a team of researchers have found two 700-year-old viral sequences in frozen caribou dung in an arctic ice patch. The group isolated part of a viral RNA genome and the complete genome of a DNA virus. Then they infected living plants with the DNA virus, what could go wrong?... Read more »
Ng, T., Chen, L., Zhou, Y., Shapiro, B., Stiller, M., Heintzman, P., Varsani, A., Kondov, N., Wong, W., Deng, X.... (2014) Preservation of viral genomes in 700-y-old caribou feces from a subarctic ice patch. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1410429111
Halloween has put me in the mood to talk about slasher movies. Once I got to looking around, I found more papers on the topic than I thought I would. I gotta warn you, this is a long read, so grab some popcorn and settle in for some slasher movie fun.If you are a fan of horror films then you know Randy Meek’s “Rules that one must abide by to successfully survive a horror movie”: (1) You can never have sex…big no-no, sex equals death, (2) you can never drink or do drugs…it’s the sin-f........ Read more »
Wee, Valerie. (2005) The Scream Trilogy, "Hyperpostmodernism," and the Late-Nineties Teen Slasher Film. Journal of Film and Video, 57(3), 44-61. info:/
Rathgeb, Douglas L. (1991) Bogeyman from the ID: Nightmare and Reality in Halloween and A Nightmare on Elm Street. Journal of Popular Film and Television, 19(1), 36-43. DOI: 10.1080/01956051.1991.9944106
Connelly, K. (2007) Defeating the Male Monster in Halloween and Halloween H2O. Journal of Popular Film and Television, 35(1), 12-21. DOI: 10.3200/JPFT.35.1.12-21
Cowan, G., & O'Brien, M. (1990) Gender and survival vs. death in slasher films: A content analysis. Sex Roles, 23(3-4), 187-196. DOI: 10.1007/BF00289865
Richard Nowell. (2011) "There's More Than One Way to Lose Your Heart": The American Film Industry, Early Teen Slasher Films, and Female Youth. Cinema Journal, 51(1), 115-140. DOI: 10.1353/cj.2011.0073
Ryan Lizardi. (2010) “Re-Imagining” Hegemony and Misogyny in the Contemporary Slasher Remake. Journal of Popular Film and Television, 38(3), 113-121. DOI: 10.1080/01956051003623464
Harris, M., & Bennett, K. (2004) You Can't Kill the Boogeyman: Halloween III and the Modern Horror Franchise. Journal of Popular Film and Television, 32(3), 98-120. DOI: 10.3200/JPFT.32.3.98-120
Humans commonly display a circadian rhythm preference for getting up early in the morning or staying up late at night (night owls).This sleep timing, or diurnal preference appears to have genetic contributions.Additionally, diurnal preference may contribute to risk for alcohol consumption as more alcohol is consumed later in the day and during the night time.Nathaniel Watson and colleagues at the University of Washington and the University of Texas recently explored the relationship between diur........ Read more »
Watson NF, Buchwald D, & Harden KP. (2013) A twin study of genetic influences on diurnal preference and risk for alcohol use outcomes. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 9(12), 1333-9. PMID: 24340296
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