Post List

  • August 10, 2014
  • 01:30 AM
  • 116 views

Reducing Risk and Creating More Resilient Supply Chains

by Andreas Wieland in Supply Chain Management Research

That does a supply chain risk researcher’s heart good: MIT Sloan Management Review has recently published two interesting case studies about the interface between risk and supply chain management. First, in the magazine’s spring issue, Chopra and Sodhi call attention to a dilemma faced by most managers: “Solutions to reduce risk mean little unless they […]... Read more »

Chopra, S., & Sodhi, M.S. (2014) Reducing the Risk of Supply Chain Disruptions. MIT Sloan Management Review. info:/

  • August 9, 2014
  • 01:45 PM
  • 381 views

Marijuana and the Developing Brain

by Gabriel in Lunatic Laboratories

You can’t get away from it, the big marijuana debate here in the US. Is it good? Is it bad? What are other countries doing? There are also a lot of claims made about marijuana, most of which aren’t true, namely the big medical claims. Then there is the other side of that fence, what about some of the health issues that are claimed, where does science sit on that?[…]... Read more »

Giedd JN, Blumenthal J, Jeffries NO, Rajapakse JC, Vaituzis AC, Liu H, Berry YC, Tobin M, Nelson J, & Castellanos FX. (1999) Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Progress in neuro-psychopharmacology , 23(4), 571-88. PMID: 10390717  

Giedd, J. N. (2004) Structural magnetic resonance imaging of the adolescent brain. Adolescent Brain Development: Vulnerabilities and Opportunities. info:/

Choo EK, Benz M, Zaller N, Warren O, Rising KL, & McConnell KJ. (2014) The impact of state medical marijuana legislation on adolescent marijuana use. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 55(2), 160-6. PMID: 24742758  

Joffe A, American Academy of Pediatrics Committee on Substance Abuse, & American Academy of Pediatrics Committee on Adolescence. (2004) Legalization of marijuana: potential impact on youth. Pediatrics, 113(6), 1825-6. PMID: 15173518  

  • August 9, 2014
  • 12:46 PM
  • 137 views

Terminal Lucidity: Myth, Mystery or Miracle?

by Neuroskeptic in Neuroskeptic_Discover

Can sick people gain mental clarity just before they die? University of Virginia researchers Michael Nahm and Bruce Greyson explore this issue in a gripping (if macabre) paper published in the journal Omega: The death of Anna Katharina Ehmer: a case study in terminal lucidity.The authors discuss the case of Anna Katharina Ehmer, a German […]The post Terminal Lucidity: Myth, Mystery or Miracle? appeared first on Neuroskeptic.... Read more »

  • August 8, 2014
  • 06:58 PM
  • 130 views

Coronavirus structural proteins and ER stress

by thelonevirologist in Virology Tidbits

The accumulation of viral proteins at the ER during an infection can induce ER stress as outlined before via three main pathways, PERK, ATF6, and IRE1, which are commonly refereed to as the unfolded Protein Response (UPR) or ER stress response. This response results in the transcriptional activation of genes encoding for ER chaperones, increasing autophagy, or regulating apoptosis.
Coronaviruses are no exception. Both structural and non-structural proteins localise to the ER - followed by the f........ Read more »

Liu DX, Fung TS, Chong KK, Shukla A, & Hilgenfeld R. (2014) Accessory proteins of SARS-CoV and other coronaviruses. Antiviral research, 97-109. PMID: 24995382  

Voss D, Pfefferle S, Drosten C, Stevermann L, Traggiai E, Lanzavecchia A, & Becker S. (2009) Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein. Virology journal, 79. PMID: 19534833  

Müller MA, van der Hoek L, Voss D, Bader O, Lehmann D, Schulz AR, Kallies S, Suliman T, Fielding BC, Drosten C.... (2010) Human coronavirus NL63 open reading frame 3 encodes a virion-incorporated N-glycosylated membrane protein. Virology journal, 6. PMID: 20078868  

Arbely E, Khattari Z, Brotons G, Akkawi M, Salditt T, & Arkin IT. (2004) A highly unusual palindromic transmembrane helical hairpin formed by SARS coronavirus E protein. Journal of molecular biology, 341(3), 769-79. PMID: 15288785  

DeDiego ML, Nieto-Torres JL, Jiménez-Guardeño JM, Regla-Nava JA, Alvarez E, Oliveros JC, Zhao J, Fett C, Perlman S, & Enjuanes L. (2011) Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis. PLoS pathogens, 7(10). PMID: 22028656  

  • August 8, 2014
  • 06:00 PM
  • 113 views

Psychiatry and inflammation (again)

by Paul Whiteley in Questioning Answers

I'd like to bring two papers to your attention in today's very quick post."The Death Star plans are not in the main computer"First up is the article by Kahn & Sommer [1] (open-access) titled: 'The neurobiology and treatment of first-episode schizophrenia'. It's about as good a read as we have so far on the topic of "brain changes in the first phase of schizophrenia" and the various management options for first-episode schizophrenia. Outside of the very important fact that "It is highly unlik........ Read more »

  • August 8, 2014
  • 03:36 PM
  • 176 views

The Self Assembling Brain

by Gabriel in Lunatic Laboratories

Let’s face it, if the brain were a lego set I would still be staring at the box wondering what I got myself into. So I guess we can just […]... Read more »

Lorenzo I. Finci et. al. (2014) The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue. Neuron. info:/http://dx.doi.org/10.1016/j.neuron.2014.07.010

  • August 8, 2014
  • 12:13 PM
  • 83 views

Melanoma, UV radiation, and TP53

by Aurelie in Coffee break Science

It’s summer, and time to get some tan. Many people flock to beaches and parks and expose as much skin as possible, bathing in sunlight – and ultraviolet (UV) radiation. Over the past decades, public health campaigns have rather successfully … Continue reading →... Read more »

Viros A, Sanchez-Laorden B, Pedersen M, Furney SJ, Rae J, Hogan K, Ejiama S, Girotti MR, Cook M, Dhomen N.... (2014) Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53. Nature, 511(7510), 478-82. PMID: 24919155  

  • August 8, 2014
  • 11:08 AM
  • 18 views

Pictures Considered #19. The Basal End of Bacterial Flagella

by Moselio Schaechter in Small Things Considered

by Elio | The end of bacterial flagella that is near the cell is a marvel of mechanical miniaturization — a molecular wheel that turns, just like the axle of a car. The assembly consists of a stator, the part that holds it in place, and a rotor, the part that…... Read more »

  • August 8, 2014
  • 10:27 AM
  • 110 views

It Only Takes Six Generations to Turn a Brown Butterfly Purple

by Elizabeth Preston in Inkfish

Evolution can seem like a slow way to get things done. It took more than a billion years for Earth’s life forms to try having more than one cell. In the famous March of Progress illustration showing an ape becoming an upright human, you can almost hear the stoop-shouldered cave guy in the middle groaning, “Hurry […]The post It Only Takes Six Generations to Turn a Brown Butterfly Purple appeared first on Inkfish.... Read more »

Wasik, B., Liew, S., Lilien, D., Dinwiddie, A., Noh, H., Cao, H., & Monteiro, A. (2014) Artificial selection for structural color on butterfly wings and comparison with natural evolution. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1402770111  

  • August 8, 2014
  • 09:52 AM
  • 120 views

Know your brain: Corpus callosum

by neurosci in Neuroscientifically Challenged







Corpus callosum (in red).CC image courtesy of Life Science Databases(LSDB).






Where is it?The corpus callosum is a large, C-shaped nerve fiber bundle found beneath the cerebral cortex. It stretches across the midline of the brain, connecting the left and right cerebral hemispheres. It makes up the largest collection of white matter tissue found in the brain.What is it and what does it do?To understand the role of the corpus callosum, it is first importan........ Read more »

  • August 8, 2014
  • 09:13 AM
  • 48 views

Translational Findings: How fruit fly research has already contributed to human health

by Bethany Christmann in Fly on the Wall

How have fruit flies already contributed to human health? I review four landmark fly papers that won their authors Nobel Prizes in Physiology or Medicine. ... Read more »

  • August 8, 2014
  • 08:40 AM
  • 100 views

The Friday Five for 8/8/2014

by Bill Sullivan in The 'Scope

Five of the best science news stories this week - mostly about junk food and junk DNA!... Read more »

  • August 8, 2014
  • 08:01 AM
  • 114 views

Researchers Uncover Stem Cell Behaviour of Human Bowel

by beredim in Stem Cells Freak

For the first time, researchers say they have uncovered new information on how stem cells in the human bowel behave, revealing vital clues about the earliest stages in bowel cancer development and how we may begin to prevent it.The research, led by Queen May University of London (QMUL) and published yesterday the journal Cell Reports, discovered how many stem cells exist within the human bowel and how they behave and evolve over time.Read More... Read more »

Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon. (2014) Ann-Marie Baker, Biancastella Cereser, Samuel Melton, Alexander G. Fletcher, Manuel Rodriguez-Justo, Paul J. Tadrous, Adam Humphries, George Elia, Stuart A.C. McDonald, Nicholas A. Wright, Benjamin D. Simons, Marnix Jansen, Trevor A. Graham. Cell Reports. info:/10.1016/j.celrep.2014.07.019

  • August 8, 2014
  • 07:27 AM
  • 130 views

Silica Glass Keeps Solar Cells Cool

by dailyfusion in The Daily Fusion

A team of scientists led by Shanhui Fan, an electrical engineering professor at Stanford University, has used a specially patterned layer of silica glass to keep solar cells cool by shepherding away unwanted thermal radiation.... Read more »

Zhu, L., Raman, A., Wang, K., Anoma, M., & Fan, S. (2014) Radiative cooling of solar cells. Optica, 1(1), 32. DOI: 10.1364/OPTICA.1.000032  

  • August 8, 2014
  • 07:26 AM
  • 100 views

Prototype Meter Tests Accuracy of Hydrogen Fuel Dispensers

by dailyfusion in The Daily Fusion

Scientists at the National Institute of Standards and Technology (NIST) have developed a prototype field test standard to test the accuracy of hydrogen fuel dispensers.... Read more »

  • August 8, 2014
  • 07:02 AM
  • 109 views

Do you believe there are Angels and Demons among us?

by Doug Keene in The Jury Room

The American Bar Association is seeking nominations until August 8, 2014 [THAT's TODAY!] to help it decide on the Top 100 law blogs (“Blawgs”). We have been in the ABA Top 100 for the past 4 years and would like to make it 5! If you like this blog, please nominate us (it’s fast and free) […]

Related posts:
Keep your eye on this one: A Depravity Scale
The Islamophobia Scale: Measuring our fear of Muslims
Cathedrals, civic buildings and your tolerance for ambiguity


... Read more »

  • August 8, 2014
  • 06:50 AM
  • 55 views

How do you prove that reading boosts IQ?

by BPS Research Digest in BPS Research Digest

A recent study on whether reading boosts intelligence attracted global media attention: "Reading at a young age makes you smarter," announced the Daily Mail. "Early reading boosts health and intelligence," said The Australian.In the race for eye-catching headlines, this mainstream media coverage arguably missed the more fascinating story of the hunt for cause and effect. Here lead author Dr Stuart Ritchie explains the science:"Causality, it turns out, is really difficult to prove. Correlational ........ Read more »

  • August 8, 2014
  • 05:54 AM
  • 72 views

Doctors should consider germline genetic testing in kidney cancer patients under 46

by Lizzie Perdeaux in BHD Research Blog

It is estimated that between 5 and 8% of kidney cancers are hereditary (Linehan et al., 2010). There are several clues that help clinicians diagnose these cases: patients who present with multifocal and/or bilateral tumours; who have a family history … Continue reading →... Read more »

Shuch B, Vourganti S, Ricketts CJ, Middleton L, Peterson J, Merino MJ, Metwalli AR, Srinivasan R, & Linehan WM. (2014) Defining early-onset kidney cancer: implications for germline and somatic mutation testing and clinical management. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(5), 431-7. PMID: 24378414  

  • August 7, 2014
  • 08:00 PM
  • 143 views

Do Narcissists Know They’re Narcissists?

by Neuroskeptic in Neuroskeptic_Discover

According to a provocative paper just published, it’s possible to accurately determine how narcissistic someone is by asking them just one thing. Here’s the question in full: To what extent do you agree with this statement: I am a narcissist? (Note: The word ‘narcissist’ means egotistical, self-focused, and vain.) Answer on a scale from 1 […]The post Do Narcissists Know They’re Narcissists? appeared first on Neuroskeptic.... Read more »

  • August 7, 2014
  • 06:16 PM
  • 70 views

In it together: Couples' life satisfaction takes a bigger hit when one partner loses their job, than when both do

by BPS Research Digest in BPS Research Digest

If your partner were to lose their job, you might think keeping your own employment would cushion the psychological blow. In fact new research finds that life satisfaction is higher for couples who share their unemployed predicament, than for couples where only one partner loses their job.Maike Luhmann and her colleagues analysed over ten years of longitudinal data from 3000 co-habiting couples in Germany, where one or both partners had gone through an unemployment. If one partner lost their job........ Read more »

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