The findings reported by Ciro Marangoni and colleagues  made for some interesting reading recently and their systematic review of longitudinal studies looking at the various environmental exposures put forward as possible risk factors pertinent to the development of bipolar disorder (BD).Trawling through the peer-reviewed material on this topic, the authors were able to 'clump' the various proposed risk factors into one of three categories: "neurodevelopment (maternal influenza during pr........ Read more »
Marangoni C, Hernandez M, & Faedda GL. (2016) The role of environmental exposures as risk factors for bipolar disorder: A systematic review of longitudinal studies. Journal of affective disorders, 165-174. PMID: 26773919
Men who use mobile phone more frequently and place their phone close to their groin have higher chances of getting abnormal sperm concentration.
Reproductive BioMedicine Online
Researchers have reported that male infertility constitutes about 30% to 40% of all infertility cases. They also reported that studies are showing continuous decline in semen quality since the start of the last century. One of the potential contributing factors in th........ Read more »
Zilberlicht, A., Wiener-Megnazi, Z., Sheinfeld, Y., Grach, B., Lahav-Baratz, S., & Dirnfeld, M. (2015) Habits of cell phone usage and sperm quality – does it warrant attention?. Reproductive BioMedicine Online, 31(3), 421-426. DOI: 10.1016/j.rbmo.2015.06.006
Depression is a serious issue for expecting mothers. Left untreated, depression could have implications for a fetus’s health. But treating the disease during pregnancy may carry health risks for the developing fetus, which makes an expecting mother’s decision whether to take medication a very difficult one. To better understand how antidepressants affect fetuses during pregnancy, scientists studied exposure in mice.
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Velasquez, J., Goeden, N., Herod, S., & Bonnin, A. (2016) Maternal Pharmacokinetics and Fetal Disposition of (±)-Citalopram during Mouse Pregnancy. ACS Chemical Neuroscience. DOI: 10.1021/acschemneuro.5b00287
In the U.S., people face 25 times more chances of being killed by guns as compared to many other developed nations.
The American Journal of Medicine
In a study on “violent death rates”, researchers have reported that the rate of gun-related murder in the U.S. is about 25 times higher as compared to 22 other high-income countries. Moreover, gun-related suicide rate in the U.S. is about 8 times more than other high-income nations;........ Read more »
Grinshteyn, E., & Hemenway, D. (2015) Violent Death Rates: The US Compared with Other High-income OECD Countries, 2010. The American Journal of Medicine. DOI: 10.1016/j.amjmed.2015.10.025
I decided to look for something I wrote that I have been wrong about. I thought about Masimo and their RAD-57. I had been very critical of Dr. Michael O’Reilly (then Executive Vice President of Masimo Corporation) for being an advocate of bad science, but he has been hired away by Apple. He should be less dangerous with a telephone than he was with the RAD-57. At the time, he wrote –... Read more »
Weaver, L., Churchill, S., Deru, K., & Cooney, D. (2012) False Positive Rate of Carbon Monoxide Saturation by Pulse Oximetry of Emergency Department Patients. Respiratory Care. DOI: 10.4187/respcare.01744
Hampson NB, & Holm JR. (2015) Suicidal carbon monoxide poisoning has decreased with controls on automobile emissions. Undersea , 42(2), 159-64. PMID: 26094291
Roderique, J., Josef, C., Feldman, M., & Spiess, B. (2015) A modern literature review of carbon monoxide poisoning theories, therapies, and potential targets for therapy advancement. Toxicology, 45-58. DOI: 10.1016/j.tox.2015.05.004
Touger, M., Birnbaum, A., Wang, J., Chou, K., Pearson, D., & Bijur, P. (2010) Performance of the RAD-57 Pulse Co-Oximeter Compared With Standard Laboratory Carboxyhemoglobin Measurement. Annals of Emergency Medicine, 56(4), 382-388. DOI: 10.1016/j.annemergmed.2010.03.041
O'Reilly, M. (2010) Performance of the Rad-57 Pulse Co-Oximeter Compared With Standard Laboratory Carboxyhemoglobin Measurement. Annals of Emergency Medicine, 56(4), 442-444. DOI: 10.1016/j.annemergmed.2010.08.016
In our part of the world, a growing proportion of fathers are rolling up their sleeves and getting involved in early child care. This has prompted increased interest from psychologists in any similarities or differences in the way that mothers and fathers interact with their children. One finding is that fathers tend to engage in more physical play, whereas mothers spend more time playing with toys and interacting socially. A new study in the Quarterly Journal of Experimental Psychology takes a ........ Read more »
Parsons, C., Young, K., Jegindoe Elmholdt, E., Stein, A., & Kringelbach, M. (2016) Interpreting infant emotional expressions: parenthood has differential effects on men and women. The Quarterly Journal of Experimental Psychology, 1-19. DOI: 10.1080/17470218.2016.1141967
Variant viewers are very popular. As we get more and more sequence data, the challenge of looking across many samples only gets more and more important. So I always like to see how different groups are doing this. I’m still waiting for the killer app on this–the pan-genome graphs with all the paths along different […]... Read more »
Cherry, J., Hong, E., Amundsen, C., Balakrishnan, R., Binkley, G., Chan, E., Christie, K., Costanzo, M., Dwight, S., Engel, S.... (2011) Saccharomyces Genome Database: the genomics resource of budding yeast. Nucleic Acids Research, 40(D1). DOI: 10.1093/nar/gkr1029
Zika. Ebola. MERS. HIV. Where Do “New” Viruses Come From?... Read more »
Forterre P. (2006) The origin of viruses and their possible roles in major evolutionary transitions. Virus research, 117(1), 5-16. PMID: 16476498
If you don't let your plants sleep at night, they die....really! Several species of plants fold their leaves up and reduce their activity at night, every night. If kept from doing that, they turn brown and shrivel up. It's called nyctinasty, and it is different from tropic movements that are directed against specifically positioned stimuli. And what directs their movements? Water! - plants are hydraulic machines.... Read more »
Ueda, M., & Nakamura, Y. (2006) Metabolites involved in plant movement and ?memory?: nyctinasty of legumes and trap movement in the Venus flytrap. Natural Product Reports, 23(4), 548. DOI: 10.1039/b515708k
A survey of homeless youth finds that pets bring benefits – and difficulties.23% of homeless youth have pets, according to research by Harmony Rhoades et al (University of Southern California). The team surveyed 398 homeless youth at two drop-in centres in Los Angeles. While previous studies have shown that pets can be very important to homeless young people, this is the first quantitative study to look at pet ownership, mental health, and the use of services amongst this group.88% of the youn........ Read more »
Rhoades, H., Winetrobe, H., & Rice, E. (2014) Pet Ownership Among Homeless Youth: Associations with Mental Health, Service Utilization and Housing Status. Child Psychiatry , 46(2), 237-244. DOI: 10.1007/s10578-014-0463-5
Sensory-targeted rehabilitation strategies (STARS) result in improvements in patient-reported and clinical outcomes. Certain deficits may be specifically targeted by different techniques.... Read more »
McKeon, P., & Wikstrom, E. (2015) Sensory-Targeted Ankle Rehabilitation Strategies for Chronic Ankle Instability. Medicine , 1. DOI: 10.1249/MSS.0000000000000859
"The average prevalence of ASD [autism spectrum disorder] was 35/10 000 children and was about 4-fold higher in males."I don't have too much to add to the findings reported by Karolina Skonieczna-Żydecka and colleagues  who estimated the prevalence of ASD in two regions of Poland: "West Pomeranian and Pomeranian regions." Based on the analysis of data from "Provincial Disability Services Commissions", researchers concluded that approximately 3 children in 1000 in those regions........ Read more »
Skonieczna-Żydecka K, Gorzkowska I, Pierzak-Sominka J, & Adler G. (2016) The Prevalence of Autism Spectrum Disorders in West Pomeranian and Pomeranian Regions of Poland. Journal of applied research in intellectual disabilities : JARID. PMID: 26771078
Between 1993 and 2015, cattle killed 13 people who were out for walks in the United Kingdom. Dozens more walkers received broken bones or other injuries from the animals.
Murderous cattle are an understudied phenomenon, say veterinarian Angharad Fraser-Williams and other researchers at the University of Liverpool in the United Kingdom. So they scoured news articles and scientific literature to learn about cattle attacks over two decades. They turned up some advice for people wishing to av........ Read more »
Inflammation is a good thing, it helps the body fight disease, and without it we wouldn't survive. Unfortunately, when inflammation isn't kept under control it can wreak havoc on the body. From potentially causing alzheimer's to arthritis it seems that unchecked inflammation can cause all sorts of issues. In fact, a new study adds to the list of issues out of control inflammation causes in the body.
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Dowell, N., Cooper, E., Tibble, J., Voon, V., Critchley, H., Cercignani, M., & Harrison, N. (2016) Acute Changes in Striatal Microstructure Predict the Development of Interferon-Alpha Induced Fatigue. Biological Psychiatry, 79(4), 320-328. DOI: 10.1016/j.biopsych.2015.05.015
Within the ground beneath our feet lie dark cavities of various shapes and sizes. They're home to pale and eyeless creatures living a midnight existence. Natural holes in the ground, filled with air and/or water, can be roughly categorized into three types based on the particular habitat they provide for subterranean organisms:(1) Caves are large, deep, and tend not to contain much organic matter for organisms to munch on. They're often found in karst and volcanic areas prone to developing big h........ Read more »
Pipan T, Fišer C, Novak T, & Culver D. (2012) Fifty years of the hypotelminorheic: What have we learned?. Acta Carsologica, 41(2-3). DOI: 10.3986/ac.v41i2-3.564
Something that is generally, and justifiably, considered negative, can, however, also be a harbinger of an underlying positive development. The case in point is the existence of so-called ‘predatory’ journals, which have – inevitably – emerged in an environment in which a true market for scientific publishing services is slowly taking shape. … Read More →... Read more »
Ding, X., Wellman, H., Wang, Y., Fu, G., & Lee, K. (2015) Theory-of-Mind Training Causes Honest Young Children to Lie. Psychological Science, 26(11), 1812-1821. DOI: 10.1177/0956797615604628
“Postmodern Stress Disorder” is considered as a relatively new psychological disorder caused by repetitive exposure to violent images and other such things.
The American Journal of Medicine
In a study by a researcher from Drexel University College of Medicine, Philadelphia, Postmodern Stress Disorder has been described as a new disorder that is almost similar to posttraumatic stress disorder, in which a person start feeling stre........ Read more »
Eiser, A. (2015) Postmodern Stress Disorder (PMSD): A Possible New Disorder. The American Journal of Medicine, 128(11), 1178-1181. DOI: 10.1016/j.amjmed.2015.04.039
Biophysical Journal has created a collection of papers that describe tools and software that can be routinely used in biological research. Editor Prof. Leslie Loew mentions that the full-text of articles in this collection will be freely available until February 25, 2016.... Read more »
Qi Y, Cheng X, Lee J, Vermaas JV, Pogorelov TV, Tajkhorshid E, Park S, Klauda JB, & Im W. (2015) CHARMM-GUI HMMM Builder for Membrane Simulations with the Highly Mobile Membrane-Mimetic Model. Biophysical journal, 109(10), 2012-22. PMID: 26588561
McGibbon RT, Beauchamp KA, Harrigan MP, Klein C, Swails JM, Hernández CX, Schwantes CR, Wang LP, Lane TJ, & Pande VS. (2015) MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories. Biophysical journal, 109(8), 1528-32. PMID: 26488642
Ribeiro AA, & Ortiz V. (2015) MDN: A Web Portal for Network Analysis of Molecular Dynamics Simulations. Biophysical journal, 109(6), 1110-6. PMID: 26143656
Hertig S, Goddard TD, Johnson GT, & Ferrin TE. (2015) Multidomain Assembler (MDA) Generates Models of Large Multidomain Proteins. Biophysical journal, 108(9), 2097-102. PMID: 25954868
Leonarski F, & Trylska J. (2015) RedMDStream: Parameterization and Simulation Toolbox for Coarse-Grained Molecular Dynamics Models. Biophysical journal, 108(8), 1843-7. PMID: 25902423
de Vries SJ, Schindler CE, Chauvot de Beauchêne I, & Zacharias M. (2015) A web interface for easy flexible protein-protein docking with ATTRACT. Biophysical journal, 108(3), 462-5. PMID: 25650913
Biedermann J, Ullrich A, Schöneberg J, & Noé F. (2015) ReaDDyMM: Fast interacting particle reaction-diffusion simulations using graphical processing units. Biophysical journal, 108(3), 457-61. PMID: 25650912
Holmes WR, Mata MA, & Edelstein-Keshet L. (2015) Local perturbation analysis: a computational tool for biophysical reaction-diffusion models. Biophysical journal, 108(2), 230-6. PMID: 25606671
It's something we're taught from a young age – when you're about to go into a rage, force yourself to count to ten and hopefully the storm will pass. This may sound like common sense, but without testing the method scientifically, how do we know if and when it really works? For example, while the counting delay could give you a chance to get a grip of your aggressive urges, it's equally plausible that it could give you time to grow even angrier about whatever triggered your displeasure in the ........ Read more »
Osgood, J., & Muraven, M. (2016) Does counting to ten increase or decrease aggression? The role of state self-control (ego-depletion) and consequences. Journal of Applied Social Psychology, 46(2), 105-113. DOI: 10.1111/jasp.12334
A quote to begin: "Taken together, there are no published evidence to suggest that there is a high overall concordance between ASD [autism spectrum disorders] and cancer or between ASD and specific cancers."Those words reported by Svend Erik Mouridsen and colleagues  (who knows a thing or two about autism research) should offer some relief to both people on the autism spectrum and their loved ones.Based on the analysis of over 100 adults "diagnosed with infantile autism (IA) in........ Read more »
Mouridsen, S., Rich, B., & Isager, T. (2016) Risk of cancer in adult people diagnosed with infantile autism in childhood: A longitudinal case control study based on hospital discharge diagnoses. Research in Autism Spectrum Disorders, 203-209. DOI: 10.1016/j.rasd.2015.12.010
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