Post List

  • May 25, 2016
  • 08:31 AM
  • 86 views

Video Tip of the Week: ProSplign in NCBI’s Genome Workbench

by Mary in OpenHelix

There are many tools at NCBI, with a huge range of functions. Literature, sequence data, variations, protein structure, chemicals and bioassays, and more. It’s hard to keep track of what’s available. Their video tutorials are helping me to be aware of new tools, and new features within existing tools. For this week’s Tip of the […]... Read more »

  • May 25, 2016
  • 07:45 AM
  • 93 views

Don't Be So Sensitive

by Mark Lasbury in As Many Exceptions As Rules

Just like some people have a tendency to go overboard, so do some immune systems. Here’s all the ways that your immune system can get it wrong and leave you with allergies – and how some allergies can save your life.... Read more »

Calboli FC, Cox DG, Buring JE, Gaziano JM, Ma J, Stampfer M, Willett WC, Tworoger SS, Hunter DJ, Camargo CA Jr, Michaud DS. (2011) Prediagnostic plasma IgE levels and risk of adult glioma in four prospective cohort studies. J Natl Cancer Inst. . DOI: 10.1093/jnci/djr361  

  • May 25, 2016
  • 04:43 AM
  • 98 views

Minimalist, anonymous rooms are probably not a good place to do teamwork

by BPS Research Digest in BPS Research Digest

According to the philosophy of "lean space management", a minimalist workspace shorn of clutter is distraction-free and ideal for productivity. But this philosophy turns out to have slim empirical foundations, and as promoting a sense of identity at work, including personalising the work space, generally leads to better outcomes, there’s reason to expect richer, characterful workplaces to be more beneficial. A new article in the Journal of Personnel Psychology builds on this past work, showing........ Read more »

Greenaway, K., Thai, H., Haslam, S., & Murphy, S. (2016) Spaces That Signal Identity Improve Workplace Productivity. Journal of Personnel Psychology, 15(1), 35-43. DOI: 10.1027/1866-5888/a000148  

  • May 25, 2016
  • 04:30 AM
  • 81 views

Position Someone to Guard Against Bad Laxity Measures

by Nicole Cattano in Sports Medicine Research (SMR): In the Lab & In the Field

Knee flexion to 90 degrees limits ankle laxity with the talar tilt test in comparison to a fully extended knee. However, knee position has no effect on anterior drawer laxity. Muscle guarding will limit our ability to accurately assess ankle laxity with a talar tilt or anterior drawer test. ... Read more »

Hanlon S, Caccese J, Knight CA, Swanik CB, & Kaminski TW. (2016) Examining Ankle-Joint Laxity Using 2 Knee Positions and With Simulated Muscle Guarding. Journal of Athletic Training, 51(2), 111-7. PMID: 26881870  

  • May 25, 2016
  • 02:52 AM
  • 79 views

The persistence of self-injury in relation to autism

by Paul Whiteley in Questioning Answers

Some behaviours associated with a diagnosis of autism don't make for great dinner table discussion. Self-injurious behaviours (SIBs), as exemplified by head banging, hair pulling and eye gouging must rank as some of the more distressing facets of [some] autism insofar as their potential effect on the person and also the people around them.These and other types of behaviour commonly headed under the category of so-called 'challenging behaviours' have tended not to be too evident when it come........ Read more »

  • May 24, 2016
  • 06:22 PM
  • 69 views

Does ecology affect human behavior? Book Review

by Farid Pazhoohi in Epistemophil

In their book The Parasite-Stress Theory of Values and Sociality, Randy Thornhill, Distinguished Professor at The University of New Mexico, and Corey L. Fincher, Assistant Professor at University of Warwick, present a new interpretation of human values and cultural behaviors, on the basis of ecological variations in parasite-stress prevalence across and within nations. Before delineating […]... Read more »

Pazhoohi, F. (2016) The Parasite-Stress Theory of Values and Sociality, Infectious Disease, History and Human Values Worldwide (Book Review). Canadian Studies in Population, 43(1-2), 155-157. info:/

  • May 24, 2016
  • 02:31 PM
  • 74 views

Hatching Sea Turtles Get a Hand from Their Siblings

by Elizabeth Preston in Inkfish



Smashing out of its egg is only the first step in a baby sea turtle's grueling early days. The turtle fights free of its eggshell only to find itself buried underground. It has to intuit which way is up, then dig out of the packed sand. As soon as it breaks onto the surface of the beach, it begins a mad sprint to the ocean. All around are its brothers and sisters, flailing toward the water as fast as their own flippers will carry them. In the sea they'll keep swimming frantically, trying ........ Read more »

  • May 24, 2016
  • 01:14 PM
  • 96 views

Raising The Standards Of Open Access Journals

by Nesru Koroso in United Academics

The Directory of Open Access Journals bans dubious journals from its index.... Read more »

  • May 24, 2016
  • 12:32 PM
  • 80 views

The James Earl Jones (or Barry White) Effect now applies to women too! 

by Doug Keene in The Jury Room

Almost five years ago, we wrote about research saying men with deep voices were more persuasive. Science has moved forward though and now, women can also be more persuasive when using a deeper voice. Some call it a “sultry voice”. New work tells us your voice doesn’t have be a deep and resonant baritone to […]

Related posts:
Who has the deepest voice amongst the Republican  candidates for President?
Feel the power of that deep and resonant voice!
Here’s why that movie wasn’t ........ Read more »

  • May 24, 2016
  • 11:59 AM
  • 88 views

A critical comment on “Contextual sensitivity in scientific reproducibility”

by Richard Kunert in Brain's Idea

Psychological science is surprisingly difficult to replicate (Open Science Collaboration, 2015). Researchers are desperate to find out why. A new study in the prestigious journal PNAS (Van Bavel et al., 2016) claims unknown contextual factors of psychological phenomena (“hidden moderators”) are to blame. The more an effect is sensitive to unknown contextual factors, the less […]... Read more »

Dreber, A., Pfeiffer, T., Almenberg, J., Isaksson, S., Wilson, B., Chen, Y., Nosek, B., & Johannesson, M. (2015) Using prediction markets to estimate the reproducibility of scientific research. Proceedings of the National Academy of Sciences, 112(50), 15343-15347. DOI: 10.1073/pnas.1516179112  

Van Bavel, J.J., Mende-Siedlecki, P., Brady, W.J., & Reinero, D.A. (2016) Contextual sensitivity in scientific reproducibility. PNAS. info:/

  • May 24, 2016
  • 11:27 AM
  • 77 views

ZIKV infection in mice: cell cycle defects as a cause for microcephaly?

by thelonevirologist in Virology Tidbits

Zika Virus (ZIKV) was first isolated in 1947 from a sentinel monkey in Uganda and despite sporadic local outbreaks only caused mild disease in humans. The emergence of ZIKV combined with severe pathogenicity in South America as early as 2014 however raised questions about the molecular evolution of ZIKV since ZIKV was previously only associated with arthralgia and a mild febrile illness but not neuropathological disorders including abnormal foetal brain development and Guillan-Barre Syndrome (GB........ Read more »

Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM.... (2016) Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell stem cell, 18(5), 587-90. PMID: 26952870  

Rodriguez-Morales AJ, Bandeira AC, & Franco-Paredes C. (2016) The expanding spectrum of modes of transmission of Zika virus: a global concern. Annals of clinical microbiology and antimicrobials, 13. PMID: 26939897  

Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK.... (2016) Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell, 165(5), 1081-91. PMID: 27180225  

Cugola, F., Fernandes, I., Russo, F., Freitas, B., Dias, J., Guimarães, K., Benazzato, C., Almeida, N., Pignatari, G., Romero, S.... (2016) The Brazilian Zika virus strain causes birth defects in experimental models. Nature. DOI: 10.1038/nature18296  

Deng YQ, Zhao H, Li XF, Zhang NN, Liu ZY, Jiang T, Gu DY, Shi L, He JA, Wang HJ.... (2016) Isolation, identification and genomic characterization of the Asian lineage Zika virus imported to China. Science China. Life sciences, 59(4), 428-30. PMID: 26993654  

Grant, A., Ponia, S., Tripathi, S., Balasubramaniam, V., Miorin, L., Sourisseau, M., Schwarz, M., Sánchez-Seco, M., Evans, M., Best, S.... (2016) Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling. Cell Host . DOI: 10.1016/j.chom.2016.05.009  

Ashour J, Laurent-Rolle M, Shi PY, & García-Sastre A. (2009) NS5 of dengue virus mediates STAT2 binding and degradation. Journal of virology, 83(11), 5408-18. PMID: 19279106  

Gelman A, Rawet-Slobodkin M, & Elazar Z. (2015) Huntingtin facilitates selective autophagy. Nature cell biology, 17(3), 214-5. PMID: 25720962  

Amaral N, Vendrell A, Funaya C, Idrissi FZ, Maier M, Kumar A, Neurohr G, Colomina N, Torres-Rosell J, Geli MI.... (2016) The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress. Nature cell biology, 18(5), 516-26. PMID: 27111841  

Schröder-Heurich B, Wieland B, Lavin MF, Schindler D, & Dörk T. (2014) Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(3), 1331-41. PMID: 24344331  

Uchil, P., Kumar, A., & Satchidanandam, V. (2006) Nuclear Localization of Flavivirus RNA Synthesis in Infected Cells. Journal of Virology, 80(11), 5451-5464. DOI: 10.1128/JVI.01982-05  

  • May 24, 2016
  • 10:44 AM
  • 69 views

Does Flu Vaccination Reduce Dementia Risk?

by William Yates, M.D. in Brain Posts

In my daily review of neuroscience news I ran across an article flu vaccination and dementia risk in heart failure.This study was reported at the 3rd World Congress on Acute Heart Failure by Dr. Ju-Chi Liu from Taipei Medical University.So how might influenza vaccination be related to dementia risk?  We do know acute influenza infection reaches the brain causing headache and increasing brain inflammation, at least temporarily. We also know brain inflammation may be involved in the mechanism........ Read more »

  • May 24, 2016
  • 10:02 AM
  • 65 views

Should Biologists be Guided by Beauty?

by Jalees Rehman in The Next Regeneration

One key characteristic of a beautiful scientific theory is the simplicity of the underlying concepts. According to Weinberg, Einstein's theory of gravitation is described in fourteen equations whereas Newton's theory can be expressed in three. Despite the appearance of greater complexity in Einstein's theory, Weinberg finds it more beautiful than Newton's theory because the Einsteinian approach rests on one elegant central principle – the equivalence of gravitation and ........ Read more »

Dietrich, M., Ankeny, R., & Chen, P. (2014) Publication Trends in Model Organism Research. Genetics, 198(3), 787-794. DOI: 10.1534/genetics.114.169714  

Weinberg, Steven. (1992) Dreams of a Final Theory . Vintage Books. info:/

  • May 24, 2016
  • 03:07 AM
  • 80 views

Around 1 in 5 with autism will experience seizure or seizure disorder

by Paul Whiteley in Questioning Answers

The paper by Jennifer Jaskiewicz and colleagues [1] recently offered a further important insight into the relationship between autism and seizure or seizure disorder (i.e. epilepsy).Based on the examination of records of nearly 50,000 children and young adults diagnosed with an autism spectrum disorder (ASD) compared with approximately quarter of a million 'not-autism' participants, authors reported some interesting trends. Concluding that some 19% of participants with autism experienced "s........ Read more »

Jennifer Jaskiewicz, Apryl Susi, Elizabeth Hisle-Gorman, David Dennison, Gregory Gorman, Cade Nylund, & Christine Erdie-Lalena. (2016) Quantification of Risks of Seizure in Autism. Neurology. info:/

  • May 24, 2016
  • 02:38 AM
  • 58 views

Study of firefighters shows our flexible body schema doesn't always adjust as we need it to

by BPS Research Digest in BPS Research Digest

The results could help explain some of the many injuriesincurred by firefighters each yearYour brain has a representation of where your body extends in space. It's how you know whether you can fit through a doorway or not, among other things. This representation – the "body schema" as some scientists call it – is flexible. For example if you're using a grabbing tool or swinging a tennis raquet, your sense of how far you can reach is updated accordingly. But there are limits to the accuracy a........ Read more »

  • May 23, 2016
  • 04:13 PM
  • 96 views

Extreme beliefs often mistaken for insanity, new study finds

by Dr. Jekyll in Lunatic Laboratories

In the aftermath of violent acts such as mass shootings, many people assume mental illness is the cause. After studying the 2011 case of Norwegian mass murderer Anders Breivik, researchers are suggesting a new forensic term to classify non-psychotic behavior that leads to criminal acts of violence.

... Read more »

Rahman T, Resnick PJ, & Harry B. (2016) Anders Breivik: Extreme Beliefs Mistaken for Psychosis. The journal of the American Academy of Psychiatry and the Law, 44(1), 28-35. PMID: 26944741  

  • May 23, 2016
  • 10:39 AM
  • 80 views

Emotional Processing: A Key to Depression Treatment?

by William Yates, M.D. in Brain Posts

In my last post I reported on the use of machine learning to aid in predicting response to depression treatment.Another interesting depression prediction tool is being investigated in a trial in England funded by the Oxford Health NHS Foundation Trust.This trial uses a visual facial recognition tool. The hypothesis is that early antidepressant action can be identified by changes in facial emotional recognition.This trial stems from work by Catherine Harmer Ph.D. from the University of Oxford. He........ Read more »

  • May 23, 2016
  • 07:55 AM
  • 79 views

Positive Stereotypes Are Pervasive and Powerful

by Jeremiah Stanghini in Jeremiah Stanghini

Pop quiz: hands up — how many of you think positive stereotypes are OK? I suspect that for many of you, your first reaction may have been, “well, yeah, they’re positive, right?” I can totally empathize with that shortcut, but … Continue reading →... Read more »

Czopp, A., Kay, A., & Cheryan, S. (2015) Positive Stereotypes Are Pervasive and Powerful. Perspectives on Psychological Science, 10(4), 451-463. DOI: 10.1177/1745691615588091  

  • May 23, 2016
  • 04:30 AM
  • 84 views

Females at Increased Risk of Protracted Concussion Symptoms

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Clinical factors that related with persistent postconcussion symptoms were sex, greater worsening symptoms from day of concussion to first concussion evaluation, continued activity participation, loss of consciousness, anterograde amnesia, and premorbid headaches, emotional symptoms on the day of concussion, and greater symptoms the day of the clinical examination. ... Read more »

  • May 23, 2016
  • 02:48 AM
  • 81 views

Sex-specific immune response to Candida albicans in schizophrenia and beyond

by Paul Whiteley in Questioning Answers

I have quite a bit of time for the various members of the Stanley Division of Developmental Neurovirology at Johns Hopkins on this blog. Not least because of the interesting work of one researcher in particular - Emily Severance - as a name behind some potentially very important research on how food, infection and immune function might come together in complicated conditions such as [some] schizophrenia and [some] bipolar disorder (see here and see here).Continuing their 'gut-brain' theme (........ Read more »

Severance, E., Gressitt, K., Stallings, C., Katsafanas, E., Schweinfurth, L., Savage, C., Adamos, M., Sweeney, K., Origoni, A., Khushalani, S.... (2016) Candida albicans exposures, sex specificity and cognitive deficits in schizophrenia and bipolar disorder. npj Schizophrenia, 16018. DOI: 10.1038/npjschz.2016.18  

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