The 2015 U.S. Tennis Open is in full swing and I ran into an interesting recent manuscript summarizing fatigue in tennis.Fatigue has multiple elements including changes in muscle performance, blood markers of lactic acid and other compounds as well as brain central perception factors.Long multi-set matches can last four or five hours. Obviously, at the end of this type of exertion, players have had to adjust to effects of significant fatigue.Reid and Duffield review the key elements of fatigue i........ Read more »
Reid M, & Duffield R. (2014) The development of fatigue during match-play tennis. British journal of sports medicine. PMID: 24668384
MedicalResearch.com Interview with: Dr. Ansar Hassan MD PhD Department of Cardiac Surgery New Brunswick Heart Centre Saint John Regional Hospital Saint John, New Brunswick Medical Research: What is the background for this study? What are the main findings? Dr. Hassan: … Continue reading →
The post Distance From Hospital Linked To Worse 30-Day Cardiac Surgery Outcomes appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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MedicalResearch.com Interview with:, & Dr. Ansar Hassan MD PhD. (2015) Distance From Hospital Linked To Worse 30-Day Cardiac Surgery Outcomes. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Beate W. Hygen PhD Student Department of Psychology Norwegian University of Science and Technology Social Science Medical Research: What is the background for this study? Response: The study is part of the Trondheim Early Secure Study (TESS) conducted … Continue reading →
The post Gene Variant May Explain Why Some Children Respond More Aggressively To Stress appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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MedicalResearch.com Interview with:, & Sameek Roychowdhury, MD, PhD. (2015) Gene Variant May Explain Why Some Children Respond More Aggressively To Stress. MedicalResearch.com. info:/
The ENCODE project began many years ago, with a pilot phase, that examined just 1% of the human genome. But this initial exploration helped the consortium participants to iron out some of the directions for later stages–including focusing on specific cell lines, techniques, and technologies in Phase 2. There have been a number of publications […]... Read more »
Malladi, V., Erickson, D., Podduturi, N., Rowe, L., Chan, E., Davidson, J., Hitz, B., Ho, M., Lee, B., Miyasato, S.... (2015) Ontology application and use at the ENCODE DCC. Database. DOI: 10.1093/database/bav010
, . (2011) A User's Guide to the Encyclopedia of DNA Elements (ENCODE). PLoS Biology, 9(4). DOI: 10.1371/journal.pbio.1001046
MedicalResearch.com Interview with: Sameek Roychowdhury, MD, PhD Assistant Professor, Internal Medicine, College of Medicine Assistant Professor, Department of Pharmacology College of Pharmacy Department of Internal Medicine Division of Medical Oncology Wexner Medical Center The Ohio State University Medical Research: What … Continue reading →
The post Cancer Driver Log Facilitates Precision Medicine, Linking Providers With Genetic Data Bank appeared first on MedicalResearch.com Medi........ Read more »
Sameek Roychowdhury, MD, PhD. (2015) Cancer Driver Log Facilitates Precision Medicine, Linking Providers With Genetic Data Bank . MedicalResearch.com. info:/
After the Great Earthquake in Japan, preparation was key to evacuating with pets - including training and socialization.When the magnitude 9 earthquake struck Japan in 2011, causing a tsunami and subsequent accident at the Fukushima nuclear plant, over 15,000 people were killed. Many people had to evacuate at short notice. In 2012, pet owners from two of the most badly affected areas, Iwate and Fukushima Prefectures, were asked about whether or not they took their pet and the types of planning t........ Read more »
Heath, S.E., & Linnabary, R.D. (2015) Challenges of managing animals in disasters in the US. Animals, 5(2), 173-192. info:/10.3390/ani5020173#sthash.7n7gGyyg.dpuf
Thompson, K.,, Every, D., Rainbird, S., Cornell, V., Smith, B., & Trigg, J. (2014) No pet or their person left behind: Increasing the disaster resilience of vulnerable groups through animal attachment, activities and networks. Animals , 4(2), 214-240. info:/10.3390/ani4020214
A survey of companion-animal owners affected by the East Japan Great Earthquake in Iwate and Fukushima Prefectures, Japan. (2015) Yamazaki, S. Anthrozoos, 28(2). info:/
Spies try to look boring, but in reality they are much more interesting than the average Joe. So it is with dizygotic twins; monozygotic twins (“identical”) get all the glory, but they’re just a split egg, any female can do it. But dizygotic twins – certain families have more, Nigerian women have more, older women have more, taller women and overweight women have more. Now there’s something that looks boring but must be interesting.... Read more »
Simpson, C., Robertson, D., Al-Musawi, S., Heath, D., McNatty, K., Ritter, L., Mottershead, D., Gilchrist, R., Harrison, C., & Stanton, P. (2014) Aberrant GDF9 Expression and Activation Are Associated With Common Human Ovarian Disorders. The Journal of Clinical Endocrinology , 99(4). DOI: 10.1210/jc.2013-3949
Palmer, J., Zhao, Z., Hoekstra, C., Hayward, N., Webb, P., Whiteman, D., Martin, N., Boomsma, D., Duffy, D., & Montgomery, G. (2006) Novel Variants in Growth Differentiation Factor 9 in Mothers of Dizygotic Twins. The Journal of Clinical Endocrinology , 91(11), 4713-4716. DOI: 10.1210/jc.2006-0970
Steinman G. (2006) Mechanisms of twinning: VIII. Maternal height, insulinlike growth factor and twinning rate. The Journal of reproductive medicine, 51(9), 694-8. PMID: 17039697
Aladashvili-Chikvaidze N, Kristesashvili J, & Gegechkori M. (2015) Types of reproductive disorders in underweight and overweight young females and correlations of respective hormonal changes with BMI. Iranian journal of reproductive medicine, 13(3), 135-40. PMID: 26000003
Hoekstra, C., Willemsen, G., van Beijsterveldt, C., Lambalk, C., Montgomery, G., & Boomsma, D. (2010) Body composition, smoking, and spontaneous dizygotic twinning. Fertility and Sterility, 93(3), 885-893. DOI: 10.1016/j.fertnstert.2008.10.012
Groeneveld, E., Lambers, M., Stakelbeek, M., Mooij, T., van den Belt-Dusebout, A., Heymans, M., Schats, R., Hompes, P., Hoek, A., Burger, C.... (2012) Factors associated with dizygotic twinning after IVF treatment with double embryo transfer. Human Reproduction, 27(10), 2966-2970. DOI: 10.1093/humrep/des258
MedicalResearch.com Interview with: Benjamin N. Breyer MD, MAS, FACS Associate Professor in Residence Department of Urology University of California, San Francisco Chief of Urology, San Francisco General Hospital Director, UCSF Male Genitourinary Reconstruction and Trauma Surgery Fellowship Medical Research: What … Continue reading →
The post Serious Injuries Rise As Older Age Groups Takes Up Cycling appeared first on MedicalResearch.com Medical Research Studies with Intervie........ Read more »
MedicalResearch.com Interview with:, & Benjamin N. Breyer MD, MAS, FACS. (2015) Serious Injuries Rise As Older Age Group Takes Up Cycling. MedicalResearch.com. info:/
LHCP 2015 is going on at St. Peterburg and new results were presented by the two main collaborations at CERN. CMS and ATLAS combined the results from run 1 and improved the quality of the measured data of the Higgs particle discovered on 2012. CERN press release is here. I show you the main picture about […]... Read more »
Marco Frasca. (2015) A theorem on the Higgs sector of the Standard Model. arxiv. arXiv: 1504.02299v1
I was intrigued by the results reported by Catherine Best and colleagues  recently and the suggestion that yet another sweeping generalisation attributed to autism (or at least autistic traits) might turn out to be not as accurate or universal as we might have all been led to believe.Based on the analysis of data from over 300 people who completed an on-line questionnaire (anonymously) measuring autistic traits, researchers reported that creative ideas as measured by a divergent thinking task........ Read more »
Best, C., Arora, S., Porter, F., & Doherty, M. (2015) The Relationship Between Subthreshold Autistic Traits, Ambiguous Figure Perception and Divergent Thinking. Journal of Autism and Developmental Disorders. DOI: 10.1007/s10803-015-2518-2
College students with chronic ankle instability have lower activity levels and more symptoms than healthy students. Activity levels appear to be related to the amount of ankle laxity.... Read more »
Hubbard-Turner, T., & Turner, M. (2015) Physical Activity Levels in College Students With Chronic Ankle Instability. Journal of Athletic Training, 2147483647. DOI: 10.4085/1062-6050-50.3.05
Medicalresearch.com Interview with: Roger Packer MD Senior Vice President Center for Neuroscience & Behavioral Health Children’s National Medical Center Washington, D.C. MedicalResearch: What is the background for this study? What are the main findings? Dr. Packer: The background is … Continue reading →
The post Genetic Signatures May Lead To Precision Treatments For Childhood Brain Tumors appeared first on MedicalResearch.com Medical Research Studies with Interviews........ Read more »
Medicalresearch.com Interview with:, & Roger Packer MD. (2015) Genetic Signatures May Lead To Precision Treatments For Childhood Brain Tumors . MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Sean Barnes Ph.D. Department of Decision, Operations & Information Technologies Robert H. Smith School of Business University of Maryland, College Park, MD Medical Research: What is the background for this study? What are the main … Continue reading →
The post Data-Driven Model Can Help Predict Hospital Discharges appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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MedicalResearch.com Interview with:, & Dr. Sean Barnes Ph.D. (2015) Data-Driven Model Can Help Predict Hospital Discharges. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Fabrice Jollant, MD, PhD McGill University, Department of Psychiatry & Douglas Mental Health University Institute McGill Group for Suicide Studies Montréal (Québec), Canada Medical Research: What is the background for this study? What are the main findings? … Continue reading →
The post Risky Decision Making May Run in Families Prone To Suicide appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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MedicalResearch.com Interview with:, & Fabrice Jollant, MD, PhD. (2015) Risky Decision Making May Run in Families Prone To Suicide. MedicalResearch.com. info:/
Everyone dreams - even people who believe that they "never dream" and can't remember any of their dreams. That's according to a group of French researchers writing in the Journal of Sleep Research: Evidence that non-dreamers do dream.
In questionnaire surveys, up to 6.5% of people report that they 'never dream'. Although most of these people report having dreamed at some point in the past, roughly 1 in every 250 people say that they can't remember ever dreaming - not even once.
But... Read more »
Herlin B, Leu-Semenescu S, Chaumereuil C, & Arnulf I. (2015) Evidence that non-dreamers do dream: a REM sleep behaviour disorder model. Journal of sleep research. PMID: 26307463
MedicalResearch.com Interview with: George L. Bakris MD Professor of Medicine Director, Comprehensive Hypertension Center University of Chicago Medicine Medical Research: What is the background for this study? What are the main findings? Dr. Bakris: Aldosterone receptor antagonists such as spironolactone are … Continue reading →
The post Finerenone Reduces Urine Protein Loss in Diabetic Kidney Disease appeared first on MedicalResearch.com Medical Research Studies with Interviews and........ Read more »
MedicalResearch.com Interview with:, & George L. Bakris MD. (2015) Finerenone Reduces Urine Protein Loss in Diabetic Kidney Disease. MedicalResearch.com. info:/
What makes someone better at switching between different tasks? Looking for the mechanisms behind cognitive flexibility, researchers have used brain scans to shed new light on this question. By studying networks of activity in the brain’s frontal cortex, a region associated with control over thoughts and actions, the researchers have shown that the degree to which these networks reconfigure themselves while switching from task to task predicts people’s cognitive flexibility.... Read more »
Uddin LQ, Supekar KS, Ryali S, & Menon V. (2011) Dynamic reconfiguration of structural and functional connectivity across core neurocognitive brain networks with development. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(50), 18578-89. PMID: 22171056
Mary Poppins taught us that a spoonful of sugar makes the medicine go down. A bumblebee's favorite sugary drink may already be laced with medicine. And bees seem to dose themselves with medicinal nectar when they're suffering from a gut full of parasites.
Plants manufacture many chemical compounds to defend against attackers. Some of these are familiar to humans—like capsaicin, the potent weapon made by chili pepper plants. But not every animal enjoys painful food experiences like we do........ Read more »
Richardson, L., Bowers, M., & Irwin, R. (2015) Nectar chemistry mediates the behavior of parasitized bees: consequences for plant fitness. Ecology, 2147483647. DOI: 10.1890/15-0263.1
by Xiaofei Sun in the Node
The process of embryo implantation consists of multiple steps: blastocyst apposition, adhesion to uterine luminal epithelial (LE) cells, and removal of the epithelial cells encasing the blastocysts. How the blastocyst trophectoderm breaches the luminal epithelial barrier has been studied for decades, the mechanism of the abstraction of LE cells was not clearly understood. Since the[...]
The post The blastocyst achieves on-time implantation by entosis appeared first on the Node.
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Cha J, Bartos A, Park C, Sun X, Li Y, Cha SW, Ajima R, Ho HY, Yamaguchi TP, & Dey SK. (2014) Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling. Cell reports, 8(2), 382-92. PMID: 25043182
Cha J, Sun X, & Dey SK. (2012) Mechanisms of implantation: strategies for successful pregnancy. Nature medicine, 18(12), 1754-1767. PMID: 23223073
Cross JC. (2005) How to make a placenta: mechanisms of trophoblast cell differentiation in mice--a review. Placenta. PMID: 15837063
Daikoku T, Cha J, Sun X, Tranguch S, Xie H, Fujita T, Hirota Y, Lydon J, DeMayo F, Maxson R.... (2011) Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Developmental cell, 21(6), 1014-25. PMID: 22100262
Finn CA, & Hinchliffe JR. (1964) Reaction of the Mouse Uterus during Implantation and Deciduoma Formation as Demonstrated by Changes in the Distribution of Alkaline Phosphatase. Journal of reproduction and fertility, 331-338. PMID: 14248593
Finn CA, & McLaren A. (1967) A study of the early stages of implantation in mice. Journal of Reproduction and Fertility, 259-267. info:/10.1530/jrf.0.0130259
Joswig A, Gabriel HD, Kibschull M, & Winterhager E. (2003) Apoptosis in uterine epithelium and decidua in response to implantation: evidence for two different pathways. Reproductive biology and endocrinology, 44. PMID: 12801416
Krehbiel RH. (1937) Cytological Studies of the Decidual Reaction in the Rat during Early Pregnancy and in the Production of Deciduomata. Physiological Zoology, 212-234. info:/
Li Y, Sun X, & Dey SK. (2015) Entosis allows timely elimination of the luminal epithelial barrier for embryo implantation. Cell reports, 11(3), 358-365. PMID: 25865893
Parr EL, Tung HN, & Parr MB. (1987) Apoptosis as the mode of uterine epithelial cell death during embryo implantation in mice and rats. Biology of reproduction, 36(1), 211-225. PMID: 3567276
Sun X, Zhang L, Xie H, Wan H, Magella B, Whitsett JA, & Dey SK. (2012) Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation. Proceedings of the National Academy of Sciences of the United States of America, 109(4), 1145-1150. PMID: 22233806
Wang H, & Dey SK. (2006) Roadmap to embryo implantation: clues from mouse models. Nature reviews. Genetics, 7(3), 185-199. PMID: 16485018
Medical Research: What is the background for this study? What are the main findings? Response: Plague, a bacterial disease that is endemic to the Western United States, is most famous for the destruction it caused during the Middle Ages when … Continue reading →
The post Recent Spike in Plague Cases in Western US appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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MedicalResearch.com Interview with:, & Natalie Kwit DVM. (2015) Recent Spike in Plague Cases in Western US. MedicalResearch.com. info:/
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