Patients should attain all objective criteria goals prior to returning to sport. A professional athlete who fails to meet functional criteria for return-to-sport or who has a low hamstring:quadriceps ratio is at greater risk for an anterior cruciate ligament graft rupture.... Read more »
Kyritsis, P., Bahr, R., Landreau, P., Miladi, R., & Witvrouw, E. (2016) Likelihood of ACL graft rupture: not meeting six clinical discharge criteria before return to sport is associated with a four times greater risk of rupture. British Journal of Sports Medicine. DOI: 10.1136/bjsports-2015-095908
I have to say that I initially felt slightly uncomfortable reading the study results published by Jillian Austin and colleagues  providing "preliminary validation for the use of autism disclosure cards in buffering negative judgment." Uncomfortable because, despite the fact that it is human nature for people to stop, stare and perhaps question something when it seems 'out of the ordinary', the idea that when children with autism specifically 'misbehave' in a public place their parents need to........ Read more »
Austin JE, Zinke VL, & Davies WH. (2016) Influencing Perception About Children with Autism and their Parents Using Disclosure Cards. Journal of autism and developmental disorders. PMID: 27241346
Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy. The results show that a particular type of protein called integrin is present on the stem cell surface and used by stem cells to interact with, or "sense" their surroundings.
... Read more »
Rozo, M., Li, L., & Fan, C. (2016) Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nature Medicine. DOI: 10.1038/nm.4116
Running Economy and Foot Strike Pattern... Read more »
Nichols, R., Germano, C., Burke, M., Nolan, K., Youngs-Grand, K., & Girard, J. (2016) The effects of foot strike on running economy in distance runners: a narrative review. Physical Therapy Reviews, 1-6. DOI: 10.1080/10833196.2016.1193970
A paper makes the remarkable claim that autism could be detected through the use of ultrasound to peer beneath the skull. This paper is from 2014, but it just came to my attention.
The authors of the piece, James Jeffrey Bradstreet, Stefania Pacini and Marco Ruggiero, studied 23 children with autism and 15 control children, who were unaffected siblings of the autistic group. Using ultrasound, the authors looked under the skull overlaying the brain's temporal cortex. The ultrasound reveale... Read more »
Bradstreet JJ, Pacini S, & Ruggiero M. (2014) A New Methodology of Viewing Extra-Axial Fluid and Cortical Abnormalities in Children with Autism via Transcranial Ultrasonography. Frontiers in human neuroscience, 934. PMID: 24459462
Scientific work is unfairly perceived by many people as a solitary, even lonely enterprise, concerned with abstracted goals rather than helping others. While some scientific work calls for a quiet room (at the least, noise-cancelling headphones), the reality is that the enterprise as a whole involves plenty of communal aspects, from collaboration and discussions to teaching and mentoring. In new research published in the Journal of Applied Psychology, researchers from the University of Miami hav........ Read more »
Clark, E., Fuesting, M., & Diekman, A. (2016) Enhancing interest in science: exemplars as cues to communal affordances of science. Journal of Applied Social Psychology. DOI: 10.1111/jasp.12392
Heavy metal band Black Label Society on stage Brazil, via Flickr/FockaListening to songs about death and dressing yourself in t-shirts featuring skulls and demons might seem like a strange way to combat existential angst. Nonetheless, a new study in Psychology of Popular Media Culture shows that listening to heavy metal helps fans of the genre deal with their own mortality. This is likely because to fans, heavy metal represents so much more than a genre, it embodies a way of life and a sense of ........ Read more »
Kneer, J., & Rieger, D. (2016) The memory remains: How heavy metal fans buffer against the fear of death. Psychology of Popular Media Culture, 5(3), 258-272. DOI: 10.1037/ppm0000072
I'm cautious about the findings reported by Daniel Blockmans & Philippe Persoons  talking about how long-term use of the stimulant medication methylphenidate (MPH) might be something to consider for at least some people diagnosed with chronic fatigue syndrome (CFS). Cautious because the sole use of a questionnaire looking "for possible improvement of concentration difficulties and fatigue" following the use of MPH on this research occasion is not exactly a top tier scientific method...Non........ Read more »
Blockmans D, & Persoons P. (2016) Long-term methylphenidate intake in chronic fatigue syndrome. Acta clinica Belgica, 1-8. PMID: 27351244
In the latest research, the authors found that a blocked schedule (presenting examples from one category at a time) outperformed an interleaved schedule (interspersing examples from all the categories) for category learning when the examples to be classified were more highly discriminable. This result was consistent across the two experiments in the study (p = 0.055 and p = 0.04). Importantly, however, although interleaving was a better strategy for learning categories of lower discriminability,........ Read more »
Noh, S., Yan, V., Bjork, R., & Maddox, W. (2016) Optimal sequencing during category learning: Testing a dual-learning systems perspective. Cognition, 23-29. DOI: 10.1016/j.cognition.2016.06.007
Parthenogenesis is the development of eggs without fertilization. For the first time, it has been shown to occur in the sterlet sturgeon. ... Read more »
Siddique MA, Butts IA, Cosson J, & Linhart O. (2016) First report on facultative parthenogenetic activation of eggs in sterlet sturgeon, Acipenser ruthenus. Animal Reproduction Science, 110-5. PMID: 26952761
Human intelligence is being defined and measured for the first time ever. Researchers have been recently undertaken to quantify the brain's dynamic functions, and identify how different parts of the brain interact with each other at different times - namely, to discover how intellect works.
... Read more »
Zhang, J., Cheng, W., Liu, Z., Zhang, K., Lei, X., Yao, Y., Becker, B., Liu, Y., Kendrick, K., Lu, G.... (2016) Neural, electrophysiological and anatomical basis of brain-network variability and its characteristic changes in mental disorders. Brain. DOI: 10.1093/brain/aww143
Whenever I'm working on a new post, I like to take a bit of time to check in on the stats for this blog. I'm particularly interested in what people are typing into their search engines to find their way here. For whatever reason, a post I wrote about what poisons smell like is very popular among users of the Internet. I'm taking this as a sign that people like to read about smells, so I thought I'd look into a couple of odour-related search queries via which people have found this blog.'type of ........ Read more »
A clinician needs to recognize that sex, competitive level, and attention deficit/hyperactivity disorder or learning disorder may influence SCAT3 scores. A medical professional could use normative conversion tables if they lack baseline scores and may not need to worry about practice effects with the SCAT3, except when retesting an athlete within 7 days.... Read more »
Chin EY, Nelson LD, Barr WB, McCrory P, & McCrea MA. (2016) Reliability and Validity of the Sport Concussion Assessment Tool-3 (SCAT3) in High School and Collegiate Athletes. The American Journal of Sports Medicine. PMID: 27281276
A quote to begin: "The AQ's [Autism Spectrum Quotient] utility for screening referrals was limited in this sample. Recommendations supporting the AQ's role in the assessment of adult ASD [autism spectrum disorder], e.g. UK NICE guidelines, may need to be reconsidered."Taken from the paper published by Ashwood and colleagues , the findings from this team don't make for great reading if you happen to be a fan of the AQ as a potential screening instrument for adult autism. Indeed,........ Read more »
Ashwood KL, Gillan N, Horder J, Hayward H, Woodhouse E, McEwen FS, Findon J, Eklund H, Spain D, Wilson CE.... (2016) Predicting the diagnosis of autism in adults using the Autism-Spectrum Quotient (AQ) questionnaire. Psychological medicine, 1-10. PMID: 27353452
Fear memory encoding, the process responsible for persistent reactions to trauma-associated cues, is influenced by a sparse but potent population of inhibitory cells called parvalbumin-interneurons (PV-INs) in the amygdala, according to a new study.
... Read more »
Lucas, E., Jegarl, A., Morishita, H., & Clem, R. (2016) Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning. Neuron. DOI: 10.1016/j.neuron.2016.06.032
Where is the periaqueductal gray?
The periaqueductal gray, or PAG, is an area of gray matter found in the midbrain. The PAG surrounds the cerebral aqueduct (hence the name periaqueductal) and occupies a column of brainstem that stretches about 14 mm long. There are no obvious visible anatomical divisions within the PAG, but researchers have divided the PAG into four columns based on differences in connectivity and function: the dorsomedial, dorsolater........ Read more »
Behbehani, M. (1995) Functional characteristics of the midbrain periaqueductal gray. Progress in Neurobiology, 46(6), 575-605. DOI: 10.1016/0301-0082(95)00009-K
by Jinhyun Cho in Language on the Move
I recently volunteered to give a presentation on the profession of translation and interpreting as a parent helper for a...... Read more »
Cho, J. (2015) Sleepless in Seoul: Neoliberalism, English fever, and linguistic insecurity among Korean interpreters. Multilingua, 34(5), 687-710. DOI: 10.1515/multi-2013-0047
Researchers have found evidence that bone marrow transplantation may one day be beneficial to a subset of patients suffering from amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder more commonly known as Lou Gehrig's disease.
... Read more »
Burberry, A., Suzuki, N., Wang, J., Moccia, R., Mordes, D., Stewart, M., Suzuki-Uematsu, S., Ghosh, S., Singh, A., Merkle, F.... (2016) Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Science Translational Medicine, 8(347), 347-347. DOI: 10.1126/scitranslmed.aaf6038
Retraction Watch reports on a strange case of alleged plagiarism.
In February 2016, F1000Research published a paper called How blockchain-timestamped protocols could improve the trustworthiness of medical science. The authors, Greg Irving and John Holden, demonstrated the use of the bitcoin blockchain as a way of publicly verifying the existence of a certain document at a certain point in time. This approach, they say, could be used to make preregistered research protocols more secure. A prob... Read more »
Irving G, & Holden J. (2016) How blockchain-timestamped protocols could improve the trustworthiness of medical science. F1000Research, 222. PMID: 27239273
"The cause of ME/CFS [myalgic encephalomyelitis/chronic fatigue syndrome] is unknown, but gut dysbiosis could be contributing to some of the symptoms and their severity. Developing therapeutic interventions aimed at reducing local inflammation, restoring gastrointestinal tract immunity and integrity and modifying the intestinal microbiome may ameliorate ME/CFS symptoms in a number of affected patients."Those were the important conclusions reported by Ludovic Giloteaux and colleagues [1........ Read more »
Giloteaux L, Goodrich JK, Walters WA, Levine SM, Ley RE, & Hanson MR. (2016) Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome. Microbiome, 4(1), 30. PMID: 27338587
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