MedicalResearch.com Interview with: Carrie C. Lubitz, MD, MPH Assistant Professor of Surgery, Harvard Medical School Senior Scientist, Institute for Technology Assessment Attending Surgeon, Mass General/North Shore Center for Outpatient Care Danvers, Massachusetts Medical Research: What is the background for this … Continue reading →
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Carrie C. Lubitz, MD, MPH. (2015) Which Resistant Hypertension Patients Should Be Screened for PA?. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Jatin J. Shah, MD Associate Professor, Department of Lymphoma/Myeloma Assistant Professor, Lymphoma/Myeloma Division of Cancer Medicine The University of Texas, MD Anderson Cancer Center Houston, TX Medical Research: What is the background for this study? What are … Continue reading →
The post New Enzyme Inhibitor Shows Modest Effect Against Relapsed Lymphoma appeared first on MedicalResearch.com.
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Dr. Jatin J. Shah, MD. (2015) New Enzyme Inhibitor Shows Modest Effect Against Relapsed Lymphoma. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Prof. Peter J. Rogers PhD School of Experimental Psychology University of Bristol, Bristol, UK Medical Research: What is the background for this study? Prof. Rogers: In recent years low-calorie sweeteners have been in the headlines because of … Continue reading →
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Prof. Peter J. Rogers PhD. (2015) Low Calorie Sweeteners Not Linked To Weight Gain. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Frederick W. Vonberg, MA, MBBS Research Fellow in Neurocritical Care Boston Children’s Hospital and Harvard Medical School Medical Research: What is the background for this study? What are the main findings? Response: An association between schizophrenia and epilepsy has long … Continue reading →
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Frederick W. Vonberg, MA, MBBS. (2015) Study Supports Shared Biology Between Schizophrenia and Epilepsy. MedicalResearch.com. info:/
When people are listening to music, their emotional reactions to the music are reflected in changes in their pupil size. Researchers from the University of Vienna and the University of Innsbruck, Austria, are the first to show that both the emotional content of the music and the listeners’ personal involvement with music influence pupil dilation. This study demonstrates that pupil size measurement can be effectively used to probe listeners’ reactions to music.... Read more »
Gingras, B., Marin, M., Puig-Waldmüller, E., & Fitch, W. (2015) The Eye is Listening: Music-Induced Arousal and Individual Differences Predict Pupillary Responses. Frontiers in Human Neuroscience. DOI: 10.3389/fnhum.2015.00619
In mountainous regions throughout much of Europe and Asia there grows an evergreen shrub by the name of Juniperus sabina (savin juniper). Being a juniper, it produces berry-like cones and is occasionally infected by members of everyone's favourite genus of sinister orange tentacled fungi, Gymnosporangium.This shrub takes no prisoners (Source)Crushing the leaves of J. sabina produces a strong unpleasant odour, a harbinger of the ability of the plant to poison many of the creatures who consume it......... Read more »
Gao R, Gao C, Tian X, Yu X, Di X, Xiao H, & Zhang X. (2004) Insecticidal activity of deoxypodophyllotoxin, isolated from Juniperus sabina L, and related lignans against larvae of Pieris rapae L. Pest Management Science, 60(11), 1131-1136. DOI: 10.1002/ps.922
Sunset in Blanchard, OK courtesy of Dr. Tim YatesThere is a significant need for improvement in the tools available for screening for cognitive impairment in a variety of disorders in neuroscience medicine.The Mini-Mental State Examination Score (MMSE) is a widely used 30-item scale for screening dementia and other neurological conditions.However, the MMSE has some significant weaknesses for use in the clinical setting.Jin Qiao and colleagues from China recently published a study testing th........ Read more »
Qiao J, Zheng X, Wang X, Lu W, Cao H, & Qin X. (2015) Neuropsychological profile in Chinese patients with Parkinson's disease and normal global cognition according to Mini-Mental State Examination Score. International journal of clinical and experimental medicine, 8(8), 13755-61. PMID: 26550322
MedicalResearch.com Interview with: Prof. Julia Hippisley-Cox PhD Professor of Clinical Epidemiology & General Practice Faculty of Medicine & Health Sciences The University of Nottingham Medical Research: What is the background for this study? What are the main findings? Prof. Hippisley–Cox: Patients with … Continue reading →
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Prof. Julia Hippisley-Cox PhD. (2015) New Tool Predicts Risk of Blindness and Amputation in Diabetes. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Aouatef Bellamine, Ph.D Lonza Inc Medical Research: What is the background for this study? What are the main findings? Dr. Bellamine: About two years ago, Robert Koeth and his colleagues (Nat Med. 2013 May;19(5):576-85) published a paper linking atherosclerosis … Continue reading →
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Study Examines Link Between L-Carnitine and Atherosclerosis. (2015) Study Examines Link Between L-Carnitine and Atherosclerosis. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Lei Xu, MD, PhD Steele Laboratory of Tumor Biology Radiation Oncology Department Massachusetts General Hospital Medical Research: What is the background for this study? Dr. Lei Xu: Neurofibromatosis 2 is characterized by benign tumors that develop throughout … Continue reading →
The post Anti-VEGF Treatment Plus Radiation For Schwannoma Control appeared first on MedicalResearch.com.
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Lei Xu, MD, PhD. (2015) Anti-VEGF Treatment Plus Radiation For Schwannoma Control. MedicalResearch.com. info:/
Our memory abilities begin to diminish in some respects as early as our twenties. But the picture isn't entirely bleak. A new study published in Psychology and Aging explores the possibility that an older person's curiosity or interest in a subject can reinforce their powers of memory. Following this view, old age is associated with forgetting more of what you don't care about, but the ability to remember what matters to you is preserved or even enhanced.Shannon McGillivray and her colleagues te........ Read more »
McGillivray, S., Murayama, K., & Castel, A. (2015) Thirst for Knowledge: The Effects of Curiosity and Interest on Memory in Younger and Older Adults. Psychology and Aging. DOI: 10.1037/a0039801
Accepting the notions that (i) correlation is not necessarily the same as causation and that (ii) case-control observational studies in particular are not the best way to ascertain whether A causes B, I was rather interested in the findings reported by Ido Lurie and colleagues  and that: "Recurrent antibiotic exposure is associated with increased risk for depression and anxiety but not for psychosis."Starting from the idea that: "Changes in the microbiota (dysbiosis) were sugge........ Read more »
Lurie, I., Yang, Y., Haynes, K., Mamtani, R., & Boursi, B. (2015) Antibiotic Exposure and the Risk for Depression, Anxiety, or Psychosis. The Journal of Clinical Psychiatry. DOI: 10.4088/JCP.15m09961
A group at the Pasteur Institute succeeded in generating a bioluminescent strain of Leptospira interrogans. Their study was published last year in PLOS Neglected Tropical Diseases.The benefit of having a bioluminescent strain is that infections of small laboratory rodents can be monitored without sacrificing the animals. Instead, the animals are placed in a special whole-body imager that detects light emitted from the bodies. The location of the infection in the animals can be ........ Read more »
Ratet G, Veyrier FJ, Fanton d'Andon M, Kammerscheit X, Nicola MA, Picardeau M, Boneca IG, & Werts C. (2014) Live imaging of bioluminescent Leptospira interrogans in mice reveals renal colonization as a stealth escape from the blood defenses and antibiotics. PLoS Neglected Tropical Diseases, 8(12). PMID: 25474719
Goris MG, Kikken V, Straetemans M, Alba S, Goeijenbier M, van Gorp EC, Boer KR, Wagenaar JF, & Hartskeerl RA. (2013) Towards the burden of human leptospirosis: duration of acute illness and occurrence of post-leptospirosis symptoms of patients in the Netherlands. PloS One, 8(10). PMID: 24098528
Fanton d'Andon M, Quellard N, Fernandez B, Ratet G, Lacroix-Lamandé S, Vandewalle A, Boneca IG, Goujon JM, & Werts C. (2014) Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways. PLoS Neglected Tropical Diseases, 8(1). PMID: 24498450
MedicalResearch.com Interview with: Charuhas Thakar, MD Director, Division of Nephrology and Hypertension Professor of Medicine University of Cincinnati Medical Research: What is the background for this study? What are the main findings? “Diabetes is the major contributor to the growing burden of end-stage renal disease,” says Charuhas Thakar, MD, professor and director of the Division of Nephrology and Hypertension at the UC College of Medicine. “Acu........ Read more »
Charuhas Thakar, MD. (2015) An Episode of Acute Kidney Injury Increases Risk and Rate of End Stage Renal Failure. MedicalResearch.com. info:/
Researchers at Case Western Reserve University and the University of Michigan have produced the first image of an important human protein as it binds with ribonucleic acid (RNA), a discovery that could offer clues to how some viruses, including HIV, control expression of their genetic material. That information could lead to new strategies to block viruses from replicating, thereby limiting or halting infection.... Read more »
Morgan, C., Meagher, J., Levengood, J., Delproposto, J., Rollins, C., Stuckey, J., & Tolbert, B. (2015) The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. Journal of Molecular Biology, 427(20), 3241-3257. DOI: 10.1016/j.jmb.2015.05.009
Patent for Bozepinib approved by scientists of University of Granada
Researchers at the University of Granada, Spain, have patented Bozepinib, a drug that inhibits the growth of cancer stem cells in breast, colon and melanoma cancers.
The mechanisms of action of Bozepinib were first described in an article published in the Open Access journal Oncotarget back in 2014. The team showed that Bozepinib was able to inhibit growth and metastasis of tumors in mice without inducing toxicity. Follow........ Read more »
Ramírez A, Boulaiz H, Morata-Tarifa C, Perán M, Jiménez G, Picon-Ruiz M, Agil A, Cruz-López O, Conejo-García A, Campos JM.... (2014) HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound. Oncotarget, 5(11), 3590-606. PMID: 24946763
A recent study indicates that Antarctic sea ice is growing, but what about its long-term evolution? Read on to see what scientists have discovered about the Antarctic's future.... Read more »
Zwally JH et al. (2015) Mass gains of the Antarctic ice sheet exceed losses. Journal of Glaciology. DOI: 10.3189/2015JoG15J071
We all have our standards. For humans, it's the five-second rule. For macaques, it's "think twice before eating food off a pile of poop." The monkeys have several ways of keeping their food (sort of) clean. And the most fastidious macaques, it seems, are rewarded with fewer parasites.
On the Japanese island of Koshima, scientists have been studying Japanese macaques (Macaca fuscata) for nearly seven decades. The tiny, forested island is overrun with the monkeys, which live there naturally... Read more »
Sarabian C, & MacIntosh AJ. (2015) Hygienic tendencies correlate with low geohelminth infection in free-ranging macaques. Biology letters, 11(11). PMID: 26538539
In the run up to the 2012 US election, President Obama visited the undecided swing-states he needed to win in order to hold on to the Presidency. A new study published in the Journal of Language and Social Psychology features an analysis of the speeches he gave, together with those of his opponent Mitt Romney, and finds it’s possible to estimate the candidates’ subsequent electoral success by measuring how audiences reacted to their speeches. It also describes how speeches are intentionally ........ Read more »
Bull, P., & Miskinis, K. (2014) Whipping It Up! An Analysis of Audience Responses to Political Rhetoric in Speeches From the 2012 American Presidential Elections. Journal of Language and Social Psychology, 34(5), 521-538. DOI: 10.1177/0261927X14564466
This week’s video tip is longer than usual. But if you want to dig deeper into all the data that you know is coming in to the UCSC Genome Browser, you want to use the Table Browser. If you’ve only used the genome browser interface, you are missing a lot of opportunity to mine for […]... Read more »
Rosenbloom, K., Armstrong, J., Barber, G., Casper, J., Clawson, H., Diekhans, M., Dreszer, T., Fujita, P., Guruvadoo, L., Haeussler, M.... (2014) The UCSC Genome Browser database: 2015 update. Nucleic Acids Research, 43(D1). DOI: 10.1093/nar/gku1177
Mangan ME, Williams JM, Kuhn RM, & Lathe WC. (2014) The UCSC Genome Browser: What Every Molecular Biologist Should Know. Current Protocols in Molecular Biology., 107(19.9), 199-199. DOI: 10.1002/0471142727.mb1909s107
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