Post List

  • January 26, 2016
  • 03:35 PM
  • 77 views

Children in the Emergency Department

by Eva Alisic in Trauma Recovery

Jonas was a master tree climber. Until today. Now his left leg has a strange angle, and he has been knocked out by the fall.

Every year, millions of injured children require treatment at a hospital Emergency Department. Approximately 1 in 6 of them develop persistent stress symptoms, such as nightmares, concentration difficulties and negative thoughts.

Emergency Department doctors and nurses provide physical care but they can also support children’s emotional wellbeing. How well are ........ Read more »

  • January 26, 2016
  • 03:35 PM
  • 83 views

Children in the Emergency Department

by Eva Alisic in Trauma Recovery

Jonas was a master tree climber. Until today. Now his left leg has a strange angle, and he has been knocked out by the fall.

Every year, millions of injured children require treatment at a hospital Emergency Department. Approximately 1 in 6 of them develop persistent stress symptoms, such as nightmares, concentration difficulties and negative thoughts.

Emergency Department doctors and nurses provide physical care but they can also support children’s emotional wellbeing. How well are ........ Read more »

  • January 26, 2016
  • 03:35 PM
  • 79 views

Children in the Emergency Department

by Eva Alisic in Trauma Recovery

Jonas was a master tree climber. Until today. Now his left leg has a strange angle, and he has been knocked out by the fall.

Every year, millions of injured children require treatment at a hospital Emergency Department. Approximately 1 in 6 of them develop persistent stress symptoms, such as nightmares, concentration difficulties and negative thoughts.

Emergency Department doctors and nurses provide physical care but they can also support children’s emotional wellbeing. How well are ........ Read more »

  • January 26, 2016
  • 03:20 PM
  • 107 views

Why you should never use the term ‘the mentally ill’

by Dr. Jekyll in Lunatic Laboratories

Even subtle differences in how you refer to people with mental illness can affect levels of tolerance, a new study has found. In a first-of-its-kind study, researchers found that participants showed less tolerance toward people who were referred to as "the mentally ill" when compared to those referred to as "people with mental illness."

... Read more »

  • January 26, 2016
  • 11:11 AM
  • 114 views

New review prompts a re-think on what low sugar levels do to our thinking

by BPS Research Digest in BPS Research Digest

Glucose. Fuel for our cells, vital for life. But how fundamental is it to how we think?According to dual-systems theory (best known from Nobel laureate Daniel Kahneman’s work), low blood glucose favours the use of fast and dirty System One thinking over the deliberative, effortful System Two. Similarly, the ego depletion theory of Roy Baumeister sees glucose as a resource that gets used up whenever we resist a temptation.But the authors of a new meta-analysis published in Psychological Bulleti........ Read more »

  • January 26, 2016
  • 03:11 AM
  • 113 views

Quality of life of parents of children with autism systematically reviewed

by Paul Whiteley in Questioning Answers

"This review verified previous reports on lower QoL [quality of life] among parents of children with ASD [autism spectrum disorder] and highlighted potential areas of support."So said the findings reported by Eleni Vasilopoulou & Joy Nisbet [1] who surveyed the available peer-reviewed literature looking at "QoL among parents of children with ASD (<18 years)". They also reported on various factors potentially contributory to the reported lower QoL including "child ........ Read more »

  • January 25, 2016
  • 02:06 PM
  • 119 views

Scientists shed new light on workings of genetic regulation

by Dr. Jekyll in Lunatic Laboratories

A team of scientists has uncovered greater intricacy in protein signaling than was previously understood, shedding new light on the nature of genetic production.
... Read more »

  • January 25, 2016
  • 01:33 PM
  • 105 views

Bacteria can turn chocolate pudding green

by Rosin Cerate in Rosin Cerate

In 1994, a paper on pudding was published by a party of microbiologists plying their trade in South Africa.... Read more »

  • January 25, 2016
  • 11:55 AM
  • 75 views

Want to be a leader? Maybe you should grow a  mustache…

by Doug Keene in The Jury Room

We’re unsure if this strategy would work for women but it seems to work for men—at least in medical schools and teaching hospitals. We do presume those male leaders with mustaches do not have the sort of mustache illustrating this post but what do we know? We also tend to believe that if a woman […]

Related posts:
You wanted to be a leader! Act like one! (or else)
Gender and Leadership: When Do Women Excel?
Now, that’s a good-looking leader! (At  least, in this group.)


... Read more »

  • January 25, 2016
  • 11:52 AM
  • 129 views

Zika virus and the negligence towards health research in poor countries

by Piter Boll in Earthling Nature

by Piter Kehoma Boll About a year ago, almost nobody on the whole world was aware of the existence of a virus named Zika virus and the illness it may cause in humans, the Zika fever or Zika disease. But … Continue reading →... Read more »

  • January 25, 2016
  • 11:36 AM
  • 93 views

Death by a thousand cuts: how antibacterial clays kill

by Betty Zou in Eat, Read, Science

Researchers at Arizona State University have demonstrated for the first time the mechanism by which antibacterial clays kill bacteria. Iron and alumninum released from the clays damage the outer membrane through oxidation. Iron also enters the cell where it generates hydroxyl radicals to create oxidative stress.... Read more »

  • January 25, 2016
  • 10:28 AM
  • 97 views

For Many Women, Migraines Worsen During Menopause

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Vincent Martin, MD Professor of Internal Medicine University of Cincinnati College of Medicine Cincinnati OH Medical Research: What is the background for this study? What are the main findings? Dr. Martin: Past studies have found that … Continue reading →
The post For Many Women, Migraines Worsen During Menopause appeared first on MedicalResearch.com.
... Read more »

Dr. Vincent Martin, MD. (2016) For Many Women, Migraines Worsen During Menopause. MedicalResearch.com. info:/

  • January 25, 2016
  • 07:08 AM
  • 99 views

These 50 overweight women kept a week-long "fat stigma" diary

by BPS Research Digest in BPS Research Digest

Health psychologists are perplexed by a conundrum. With rates of obesity on the rise, experts have warned that social discrimination towards overweight people will increase. Anecdotal evidence suggests this is happening. And yet research studies have repeatedly found that overweight people typically report experiencing only a handful of stigmatising experiences in their life-times.One reason for this mismatch might be that existing studies have asked overweight people to recall from memory any t........ Read more »

Seacat, J., Dougal, S., & Roy, D. (2014) A daily diary assessment of female weight stigmatization. Journal of Health Psychology, 21(2), 228-240. DOI: 10.1177/1359105314525067  

  • January 25, 2016
  • 03:03 AM
  • 99 views

Gastrointestinal symptoms and autism yet again

by Paul Whiteley in Questioning Answers

It's been a few weeks since I last posted on the quite well-known [evidence-based] overlap that is autism and gastrointestinal (GI) symptoms. Today I'm remedying the situation by briefly discussing the findings reported by Francesca Fulceri and colleagues [1].Drawing on data from 230 preschoolers including "four groups of children... ASD individuals suffering from GI symptoms (ASD/GI+), ASD subjects without GI symptoms (ASD/GI-), TD peers with (TD/GI+) and without (TD/GI-) GI symptoms" rese........ Read more »

Fulceri F, Morelli M, Santocchi E, Cena H, Del Bianco T, Narzisi A, Calderoni S, & Muratori F. (2015) Gastrointestinal symptoms and behavioral problems in preschoolers with Autism Spectrum Disorder. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. PMID: 26748423  

  • January 24, 2016
  • 08:46 PM
  • 88 views

Recent Study Reveals Role for Bacterial Viruses in Microbiome Evolution

by Geoffrey Hannigan in Prophage

Microbial communities are fierce battlegrounds between bacteria and other microbes competing for limited resources. One method some bacteria use to kill their competitors is the production of bacteriocins...... Read more »

Nedialkova LP, Sidstedt M, Koeppel MB, Spriewald S, Ring D, Gerlach RG, Bossi L, & Stecher B. (2015) Temperate phages promote colicin-dependent fitness of Salmonella enterica serovar Typhimurium. Environmental microbiology. PMID: 26439675  

  • January 24, 2016
  • 07:16 PM
  • 96 views

http://virologytidbits.blogspot.com/2016/01/human-cytomegalovirus-hcmv-and.html

by thelonevirologist in Virology Tidbits

Human Cytomegalovirus (HCMV), the prototype member of the herpesvirus subfamily Betaherpesvirinae, is the major cause of birth defects caused by viral infections, pose a serious problem for immunocompromised patients and has more recently also been associated with the onset of artherosclerosis. Upon birth, between 0.5 and 2.5% of all newborns are infected with HCMV with up to 5% being symptomatic, i.e. presenting themselves with symptoms ranging from microcephaly, motor disabilities to chorioret........ Read more »

Shintani T, & Klionsky DJ. (2004) Autophagy in health and disease: a double-edged sword. Science (New York, N.Y.), 306(5698), 990-5. PMID: 15528435  

Decuypere JP, Parys JB, & Bultynck G. (2012) Regulation of the autophagic bcl-2/beclin 1 interaction. Cells, 1(3), 284-312. PMID: 24710477  

Espert L, Codogno P, & Biard-Piechaczyk M. (2007) Involvement of autophagy in viral infections: antiviral function and subversion by viruses. Journal of molecular medicine (Berlin, Germany), 85(8), 811-23. PMID: 17340132  

Hyttinen JM, Niittykoski M, Salminen A, & Kaarniranta K. (2013) Maturation of autophagosomes and endosomes: a key role for Rab7. Biochimica et biophysica acta, 1833(3), 503-10. PMID: 23220125  

Sun Y, Yu S, Ding N, Meng C, Meng S, Zhang S, Zhan Y, Qiu X, Tan L, Chen H.... (2014) Autophagy benefits the replication of Newcastle disease virus in chicken cells and tissues. Journal of virology, 88(1), 525-37. PMID: 24173218  

Shrivastava S, Devhare P, Sujijantarat N, Steele R, Kwon YC, Ray R, & Ray RB. (2015) Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway. Journal of virology, 90(3), 1387-96. PMID: 26581990  

Cavignac Y, & Esclatine A. (2010) Herpesviruses and autophagy: catch me if you can!. Viruses, 2(1), 314-33. PMID: 21994613  

Montagnaro, S., Ciarcia, R., Pagnini, F., De Martino, L., Puzio, M., Granato, G., Avino, F., Pagnini, U., Iovane, G., & Giordano, A. (2013) Bovine herpesvirus type 4 infection modulates autophagy in a permissive cell line. Journal of Cellular Biochemistry, 114(7), 1529-1535. DOI: 10.1002/jcb.24494  

O'Connor S, Taylor C, Campbell LA, Epstein S, & Libby P. (2001) Potential infectious etiologies of atherosclerosis: a multifactorial perspective. Emerging infectious diseases, 7(5), 780-8. PMID: 11747688  

Orvedahl A, Alexander D, Tallóczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, & Levine B. (2007) HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell host , 1(1), 23-35. PMID: 18005679  

Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, & Yu D. (2007) Human cytomegalovirus UL38 protein blocks apoptosis. Journal of virology, 81(7), 3109-23. PMID: 17202209  

Chaumorcel M, Lussignol M, Mouna L, Cavignac Y, Fahie K, Cotte-Laffitte J, Geballe A, Brune W, Beau I, Codogno P.... (2012) The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1. Journal of virology, 86(5), 2571-84. PMID: 22205736  

Matsuo J, Tsukumo Y, Sakurai J, Tsukahara S, Park HR, Shin-ya K, Watanabe T, Tsuruo T, & Tomida A. (2009) Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin. Cancer science, 100(2), 327-33. PMID: 19068091  

Matsuo J, Tsukumo Y, Saito S, Tsukahara S, Sakurai J, Sato S, Kondo H, Ushijima M, Matsuura M, Watanabe T.... (2012) Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation. Molecular cancer therapeutics, 11(5), 1082-91. PMID: 22402126  

Marschall M, Feichtinger S, & Milbradt J. (2011) Regulatory roles of protein kinases in cytomegalovirus replication. Advances in virus research, 69-101. PMID: 21762822  

Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T.... (2009) Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nature cell biology, 11(4), 385-96. PMID: 19270696  

Bhattacharjee B, Renzette N, & Kowalik TF. (2012) Genetic analysis of cytomegalovirus in malignant gliomas. Journal of virology, 86(12), 6815-24. PMID: 22496213  

  • January 24, 2016
  • 02:45 PM
  • 122 views

Treat the pain... or treat the depression? Carpal Tunnel Syndrome management

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Carpal tunnel syndrome is a very common pain disorder associated with compression of the median nerve at the carpal tunnel. Approximately 139 women and 67 males per 100,000 people will report this problem over the course of one year, although this depends on the definition used. The problem with CTS is not only that it is common, but also that it affects function - it is really difficult to carry out normal daily life with a numb or tingly hand, poor grip strength (particularly in the fingertips........ Read more »

Fernández-Muñoz, J., Palacios-Ceña, M., Cigarán-Méndez, M., Ortega-Santiago, R., de-la-Llave-Rincón, A., Salom-Moreno, J., & Fernández-de-las-Peñas, C. (2016) Pain is Associated to Clinical, Psychological, Physical, and Neurophysiological Variables in Women With Carpal Tunnel Syndrome. The Clinical Journal of Pain, 32(2), 122-129. DOI: 10.1097/AJP.0000000000000241  

  • January 24, 2016
  • 01:52 PM
  • 115 views

60 genetic disorders affect skin and nervous system

by Dr. Jekyll in Lunatic Laboratories

One of the most common genetic disorders is a condition called neurofibromatosis, which causes brown spots on the skin and benign tumors on the brain, spinal cord and other parts of the nervous system. Neurofibromatosis is one of at least 60 genetic diseases called neurocutaneous disorders that involve the skin, central nervous system, and/or peripheral nervous system.

... Read more »

Figueiredo, A., Mata-Machado, N., McCoyd, M., & Biller, J. (2016) Neurocutaneous Disorders for the Practicing Neurologist: a Focused Review. Current Neurology and Neuroscience Reports, 16(2). DOI: 10.1007/s11910-015-0612-7  

  • January 24, 2016
  • 12:56 PM
  • 64 views

Genes Identified That May Predispose Some Individuals to Getting Sick

by Marie Benz in MedicalResearch.com

  MedicalResearch.com Interview with: Ephraim L. Tsalik, MD MHS PhD Assistant Professor of Medicine Division of Infectious Diseases Center for Applied Genomics & Precision Medicine Duke University Medical Center Emergency Department Service Line Durham VA Medical Center  Medical Research: What … Continue reading →
The post Genes Identified That May Predispose Some Individuals to Getting Sick appeared first on MedicalResearch.com.
... Read more »

Dr. Ephraim L. Tsalik. (2016) Genes Identified That May Predispose Some Individual to Getting Sick. MedicalResearch.com. info:/

  • January 24, 2016
  • 11:17 AM
  • 102 views

Will climate change lead to more blizzards?

by dominicwhite in Two Degrees or Under

Snowstorms like the one that hit the east coast of North America this weekend are sometimes used by climate sceptics to argue that global warming is a hoax. “Surely we wouldn’t have seen 2 feet of snow if the temperature...... Read more »

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