I'd encourage readers interested in the background to the response paper by Michael Sharpe and colleagues  to have a look at a previous blogging occasion when the topic of the PACE trial, chronic fatigue syndrome (CFS) and 'recovery' were discussed (see here).Suffice to say that this latest paper is a reply to one published by Carolyn Wilshire and colleagues  who concluded that: "The claim that patients [with CFS] can recover as a result of CBT [cognitive behaviour therapy] ........ Read more »
M Sharpe, T Chalder, AL Johnson, KA Goldsmith, & PD White. (2017) Do more people recover from chronic fatigue syndrome with cognitive behaviour therapy or graded exercise therapy than with other treatments?. Fatigue: Biomedicine, Health , 1-5. info:/10.1080/21641846.2017.1288629
I enjoy clubbing and pop/rock concerts exclusively with my ear plugs in. Does that mean I miss out? No, I enjoy the music exactly as it is meant to be. Picture by Melianis at fi.wikipedia (CC BY 2.5) Since 2004 the urban dictionary includes the term ‘deaf rave’ to describe a ‘rave, or party, organised […]... Read more »
Huang J, Gamble D, Sarnlertsophon K, Wang X, & Hsiao S. (2013) Integration of auditory and tactile inputs in musical meter perception. Advances in experimental medicine and biology, 453-61. PMID: 23716252
Zhao F, Manchaiah VK, French D, & Price SM. (2010) Music exposure and hearing disorders: an overview. International journal of audiology, 49(1), 54-64. PMID: 20001447
Bibliometric research analyzes the use of Social Representation Theory (SRT) in Organizational Studies (OS). We investigated 90 papers published in journals and scientific events from 2001 to 2014. The results indicate that the use of SRT in OS is incipient, superficial and presents theoretical and methodological inconsistencies. … Read More →... Read more »
Martins-Silva, P., Silva Junior, A., Peroni, G., Medeiros, C., & Vitória, N. (2016) Teoria das representações sociais nos estudos organizacionais no Brasil: análise bibliométrica de 2001 a 2014. Cadernos EBAPE.BR, 14(4), 891-919. DOI: 10.1590/1679-395155900
The evolving epidemic of opioid overdose and overdose deaths is receiving increased public and research attention.Opioids overdoses and overdose deaths are often unintentional or accidental. It has been known that concurrent use of opioids with alcohol or benzodiazepines (i.e. Valium or Xanax) increases risk for overdose toxicity.A recent study published in the British Medical Journal confirmed the association of concurrent benzodiazepine prescription with opioid overdose.This research team exam........ Read more »
Sun EC, Dixit A, Humphreys K, Darnall BD, Baker LC, & Mackey S. (2017) Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis. BMJ (Clinical research ed.). PMID: 28292769
It’s been a while since we’ve had a new cognitive bias to share with you. Previously we’ve blogged on many different biases and here are a handful of those posts. Today’s research paper combines three biases—two of which we’ve blogged about before: the better-than-average effect, confirmation bias and also, the endowment effect. The endowment effect […]... Read more »
Gregg AP, Mahadevan N, & Sedikides C. (2017) The SPOT effect: People spontaneously prefer their own theories. Quarterly Journal of Experimental Psychology, 70(6), 996-1010. PMID: 26836058
Meet the Moroccan flic-flac spider (Cebrennus rechenbergi), a truly unique spider that when provoked or threatened escapes by doubling its normal walking speed using forward or backward flips similar to acrobatic flic-flac movements used by gymnasts.
C. rechenbergi is a species of huntsman spider indigenous to Morocco and can be found in the sand dunes of the Erg Chebbi desert . The spider ... Read more »
Ralf Simon King. (2013) BiLBIQ: A Biologically Inspired Robot with Walking and Rolling Locomotion. Biosystems . info:/10.1007/978-3-642-34682-8
"While pregnant women should continue to avoid handling soiled cat litter, given possible T. gondii exposure, our study strongly indicates that cat ownership in pregnancy or early childhood does not confer an increased risk of later adolescent PEs [psychotic experiences]."So said the findings reported by Francesca Solmi and colleagues  (open-access) who brought a smile to any reader of the title of their paper: "Curiosity killed the cat: no evidence of an association between cat ownershi........ Read more »
Solmi F, Hayes JF, Lewis G, & Kirkbride JB. (2017) Curiosity killed the cat: no evidence of an association between cat ownership and psychotic symptoms at ages 13 and 18 years in a UK general population cohort. Psychological medicine, 1-9. PMID: 28222824
Can’t wait to break out of high school and dash off to college? College is a lot of fun. Late nights, parties, sporting events with thousands of people, on-campus concerts and thousands of potential new friends combine to make college some of the best years of a person’s life. Yet, in the midst of all […]
Check out 3 Study Habits of Successful Students in College, an original post on Thinker Academy.
... Read more »
Hartwig, M., & Dunlosky, J. (2011) Study strategies of college students: Are self-testing and scheduling related to achievement?. Psychonomic Bulletin , 19(1), 126-134. DOI: 10.3758/s13423-011-0181-y
"In our cohort, high levels of antibodies to herpes simplex virus 2 at midpregnancy were associated with an elevated risk of autism spectrum disorder in male offspring. These findings provide support for the hypothesis that gestational infection may contribute to the pathogenesis of autism spectrum disorder and have the potential to drive new efforts to monitor women more closely for cryptic gestational infection and to implement suppressive therapy during pregnancy."That was the conclusion reac........ Read more »
Milada Mahic, Siri Mjaaland, Hege Marie Bøvelstad, Nina Gunnes, Ezra Susser, Michaeline Bresnahan, Anne-Siri Øyen, Bruce Levin, Xiaoyu Che, Deborah Hirtz.... (2017) Maternal Immunoreactivity to Herpes Simplex Virus 2 and Risk of Autism Spectrum Disorder in Male Offspring. mSphere. info:/10.1128/mSphere.00016-17
I just read a concerning paper about an experimental stem cell treatment for children with autism.
The authors are Himanshu Bansal and colleagues of India. The senior author, Prasad S Koka, is the Editor-in-Chief of the Journal of Stem Cells where the paper appeared, which raises questions about whether the manuscript received a thorough peer review. Koka is actually an author on all five of the research papers published in that issue of the journal. But that's a minor issue compared ... Read more »
Bansal H, Verma P, Agrawal A, Leon J, Sundell IB, Koka PS. (2016) A Short Study Report on Bone Marrow Aspirate Concentrate Cell Therapy in Ten South Asian Indian Patients with Autism. Journal of Stem Cells, 11(1). info:/
by Rita Handrich in The Jury Room
Here’s another this-and-that post documenting things you need to know but that we don’t want to do a whole post about–so you get a plethora of factoids that will entertain your family and entrance your co-workers. Or at least be sort of fun to read and (probably) as awe-inspiring as the stack of vegetables and […]... Read more »
Beaman, CP, Powell, K, & Rapley, E. (2015) Want to block eagworms from conscious awareness? Buy gum! . The Quarterly Journal of Experimental Psychology,, 68(6), 1049-1057. info:/
by Piter Kehoma Boll Charles Darwin had already noticed that small animals, such as those found in zooplankton, are widely distributed around the world, even those that are found in small ponds of freshwater. This seemed to go against the … Continue reading →... Read more »
Gómez, A., Serra, M., Carvalho, G., & Lunt, D. (2002) Speciation in ancient cryptic species complexes: evidence from the molecular phylogeny of Brachionus plicatilis(Rotifera). Evolution, 56(7), 1431. DOI: 10.1554/0014-3820(2002)056[1431:SIACSC]2.0.CO;2
Øie, G., Makridis, P., Reitan, K., & Olsen, Y. (1997) Protein and carbon utilization of rotifers (Brachionus plicatilis) in first feeding of turbot larvae (Scophthalmus maximus L.). Aquaculture, 153(1-2), 103-122. DOI: 10.1016/S0044-8486(96)01514-1
Suatoni, E., Vicario, S., Rice, S., Snell, T., & Caccone, A. (2006) An analysis of species boundaries and biogeographic patterns in a cryptic species complex: The rotifer—Brachionus plicatilis. Molecular Phylogenetics and Evolution, 41(1), 86-98. DOI: 10.1016/j.ympev.2006.04.025
Walker, K. (1981) 13. A synopsis of ecological information on the saline lake rotifer Brachionus plicatilis Müller 1786. Hydrobiologia, 81-82(1), 159-167. DOI: 10.1007/BF00048713
OK I'm a little confused right now.Not so long ago I talked about the paper from Horvath and colleagues  (see here) concluding that "the limited data currently available suggest that ω-3 FA [omega-3 fatty acid] supplementation does not enhance the performance of children with ASD [autism spectrum disorder]." Such a conclusion was based on the application of a systematic review and meta-analysis of the available peer-reviewed literature up to August 2016.Now however, another sy........ Read more »
Mazahery H, Stonehouse W, Delshad M, Kruger MC, Conlon CA, Beck KL, & von Hurst PR. (2017) Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials. Nutrients, 9(2). PMID: 28218722
"A personal history and a maternal history of autoimmune disease were associated with an increased risk of ADHD [attention-deficit hyperactivity disorder]. The previously reported association between type 1 diabetes and ADHD was confirmed. In addition, specific parental autoimmune diseases were associated with ADHD in offspring."So said the study results published by Nielsen and colleagues  including "a study population of 983,680 individuals followed from 1995 to 2012." Reliant once aga........ Read more »
Nielsen PR, Benros ME, & Dalsgaard S. (2017) Associations Between Autoimmune Diseases and Attention-Deficit/Hyperactivity Disorder: A Nationwide Study. Journal of the American Academy of Child and Adolescent Psychiatry, 56(3), 234-2400. PMID: 28219489
Emotional intelligence (EI) is characterized by the ability to recognize emotional states in self and in others.This emotional recognition may be helpful in guiding behavior and in improving interpersonal relationships.It seems logical on a face validity level to assume that higher levels of EI would be good in the selection of students for medical school.However, there are few studies assessing EI in physicians. There are fewer studies that examine whether EI influences physician behavior, pati........ Read more »
Shahid, R., Stirling, J., & Adams, W. (2016) Assessment of Emotional Intelligence in Pediatric and Med-Peds Residents. Journal of Contemporary Medical Education, 4(4), 153. DOI: 10.5455/jcme.20170116015415
How much damage can the brain take and still function normally? In a new paper, A Lesion-Proof Brain?, Argentinian researchers Adolfo M. García et al. describe the striking case of a woman who shows no apparent deficits despite widespread brain damage.
The patient, "CG", is 44 years old and was previously healthy until a series of strokes lesioned large parts of her brain, as shown below.
García et al. say that the damage included "extensive compromise of the right fronto-temporo-parie... Read more »
García, A., Sedeño, L., Herrera Murcia, E., Couto, B., & Ibáñez, A. (2017) A Lesion-Proof Brain? Multidimensional Sensorimotor, Cognitive, and Socio-Affective Preservation Despite Extensive Damage in a Stroke Patient. Frontiers in Aging Neuroscience. DOI: 10.3389/fnagi.2016.00335
Breast cancer (BC) is the most common cancer among women and one of the leading causes of cancer-related deaths worldwide (1-3). It is a clinically heterogeneous disease, with at least 5 different subtypes (4) and quite variable prognosis, even within a subtype. In spite of early detection programmes, unfortunately 20-30% of early stage cases will eventually experience recurrence and develop distant metastasis. However, currently, there is no acceptable method for monitoring patients who are lik........ Read more »
Martín-Sánchez E, Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, Blanco-Luquin I, Córdoba A, Vicente-García F, Pérez-Janices N, Escors D, Megías D.... (2017) CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer. Oncotarget. PMID: 28178655
Stefansson OA, Moran S, Gomez A, Sayols S, Arribas-Jorba C, Sandoval J, Hilmarsdottir H, Olafsdottir E, Tryggvadottir L, Jonasson JG.... (2015) A DNA methylation-based definition of biologically distinct breast cancer subtypes. Molecular oncology, 9(3), 555-68. PMID: 25468711
He LH, Ma Q, Shi YH, Ge J, Zhao HM, Li SF, & Tong ZS. (2013) CHL1 is involved in human breast tumorigenesis and progression. Biochemical and biophysical research communications, 438(2), 433-8. PMID: 23906755
Smith RA, Andrews K, Brooks D, DeSantis CE, Fedewa SA, Lortet-Tieulent J, Manassaram-Baptiste D, Brawley OW, & Wender RC. (2016) Cancer screening in the United States, 2016: A review of current American Cancer Society guidelines and current issues in cancer screening. CA: a cancer journal for clinicians, 66(2), 96-114. PMID: 26797525
Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thürlimann B, Senn HJ, & Panel members. (2013) Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013. Annals of oncology : official journal of the European Society for Medical Oncology, 24(9), 2206-23. PMID: 23917950
Huo D, Clayton WM, Yoshimatsu TF, Chen J, & Olopade OI. (2016) Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients. Oncotarget, 7(34), 55231-55248. PMID: 27409424
Feng W, Shen L, Wen S, Rosen DG, Jelinek J, Hu X, Huan S, Huang M, Liu J, Sahin AA.... (2007) Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast cancer research : BCR, 9(4). PMID: 17764565
Karsli-Ceppioglu S, Dagdemir A, Judes G, Ngollo M, Penault-Llorca F, Pajon A, Bignon YJ, & Bernard-Gallon D. (2014) Epigenetic mechanisms of breast cancer: an update of the current knowledge. Epigenomics, 6(6), 651-64. PMID: 25531258
Fang, C., Wei, X., Zeng, X., Wang, F., Weng, H., & Long, X. (2015) Aberrant GSTP1 promoter methylation is associated with increased risk and advanced stage of breast cancer: a meta-analysis of 19 case-control studies. BMC Cancer, 15(1). DOI: 10.1186/s12885-015-1926-1
Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, & Laird PW. (2004) Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer research, 64(11), 3807-13. PMID: 15172987
Fiegl H, Millinger S, Goebel G, Müller-Holzner E, Marth C, Laird PW, & Widschwendter M. (2006) Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Cancer research, 66(1), 29-33. PMID: 16397211
Wang L, Zeng H, Wang Q, Zhao Z, Boyer TG, Bian X, & Xu W. (2015) MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs. Science advances, 1(9). PMID: 26601288
Shen Y, Wang Z, Loo LW, Ni Y, Jia W, Fei P, Risch HA, Katsaros D, & Yu H. (2015) LINC00472 expression is regulated by promoter methylation and associated with disease-free survival in patients with grade 2 breast cancer. Breast cancer research and treatment, 154(3), 473-82. PMID: 26564482
Senchenko VN, Krasnov GS, Dmitriev AA, Kudryavtseva AV, Anedchenko EA, Braga EA, Pronina IV, Kondratieva TT, Ivanov SV, Zabarovsky ER.... (2011) Differential expression of CHL1 gene during development of major human cancers. PloS one, 6(3). PMID: 21408220
Balance assessments were not associated with anterior cruciate ligament injury risk among elite female handball and soccer athletes.
... Read more »
Steffen K, Nilstad A, Krosshaug T, Pasanen K, Killingmo A, & Bahr R. (2017) No association between static and dynamic postural control and ACL injury risk among female elite handball and football players: a prospective study of 838 players. British Journal of Sports Medicine, 51(4), 253-259. PMID: 28148513
"In 3.5-year-old children, CDA [coeliac disease autoimmunity] is associated with increased reports of child depression and anxiety, aggressive behavior, and sleep problems when mothers are unaware of their child’s CDA status."So said the findings reported by Laura Smith and colleagues  (open-access available here) adding to an emerging body of peer-reviewed research suggesting that the archetypal 'gluten is the baddie' autoimmune condition known as coeliac disease might, when not manag........ Read more »
Smith LB, Lynch KF, Kurppa K, Koletzko S, Krischer J, Liu E, Johnson SB, Agardh D, & TEDDY study group. (2017) Psychological Manifestations of Celiac Disease Autoimmunity in Young Children. Pediatrics. PMID: 28219962
On December 23, 2016, as most Australians were winding down for the holiday week ahead, Faysal Ishak Ahmed, a 27-year-old...... Read more »
Kenison TC, Madu A, Krupat E, Ticona L, Vargas IM, & Green AR. (2017) Through the Veil of Language: Exploring the Hidden Curriculum for the Care of Patients With Limited English Proficiency. Academic medicine : journal of the Association of American Medical Colleges, 92(1), 92-100. PMID: 27166864
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