Post List

  • March 6, 2017
  • 04:25 AM
  • 270 views

"Logical fallacies in animal model research"

by Paul Whiteley in Questioning Answers

A paper which is a bit 'out of left field' is presented for your reading pleasure today and how one should be rather careful about how animal research - "with focus on animal models of mental illness" - is translated into relevance to humans [1].The paper by Espen Sjoberg is pertinent to various diagnostic labels including depression and schizophrenia. I would perhaps disagree with the author including autism under the specific heading of 'mental illness' (bearing in mind various mental hea........ Read more »

Sjoberg EA. (2017) Logical fallacies in animal model research. Behavioral and Brain Functions. info:/10.1186/s12993-017-0121-8

  • March 5, 2017
  • 11:46 PM
  • 238 views

If Collectivists like Social Groups, and Cities are Social Groups, do Collectivists like Cities?

by Mark Rubin in Mark Rubin's Social Psychology Research Blog

Do you like the place where you live? Maybe its got great architecture, its clean and crime free, the housing is cheap, and/or the nightlife is good? But maybe your liking for the place is also related to something else - your own tendency to identify with social groups? In some recent research, my colleagues and I investigated this issue by considering the relations between collectivism, city identification, and city evaluation.Collectivism is a sociocultural orientation towards perceiving the ........ Read more »

  • March 5, 2017
  • 05:37 PM
  • 376 views

Do you crave music like you crave a cookie?

by Kiralee Musgrove in Neuroscientist on music

Imagine there is a cookie sitting in front of you. You are hungry. You have been on a diet for months. If you have to look at one more raw, paleo, gluten free snack you are going to scream.... Read more »

  • March 4, 2017
  • 06:23 PM
  • 190 views

More non-translatable orthotic research

by Craig Payne in Its a Foot Captain, But Not as You Know It

More non-translatable orthotic research... Read more »

  • March 4, 2017
  • 04:43 AM
  • 252 views

Fatigue in adults with a 22q11.2 deletion syndrome

by Paul Whiteley in Questioning Answers

The genetic condition called 22q11.2 deletion syndrome (22q11.2DS) has, on occasion, provided some research fodder for this blog (see here and see here). The reason for its inclusion here has tended to be around the 'overlap' in the presentation of 22q11.2 and autism/autistic features and the importance of appropriate screening as and when an autism diagnosis is received (see here). Remember: receipt of an autism diagnosis is a starting point not the finishing line.Today I'm once again talk........ Read more »

Vergaelen E, Claes S, Kempke S, & Swillen A. (2017) High prevalence of fatigue in adults with a 22q11.2 deletion syndrome. American journal of medical genetics. Part A. PMID: 28190295  

  • March 4, 2017
  • 03:22 AM
  • 223 views

Is changing footstrike pattern beneficial to runners?

by Craig Payne in Running Research Junkie

Is changing footstrike pattern beneficial to runners?... Read more »

  • March 3, 2017
  • 11:05 PM
  • 205 views

All-Atom Molecular Dynamics Simulations

by ragothamanyennamalli in Getting to know Structural Bioinformatics

With increasing computational power (aka GPU) that can be accessed these days, it is no wonder that performing all-atom molecular dynamics simulation for a longer time, with duplicates and/or triplicates, has become easier.... Read more »

  • March 3, 2017
  • 03:48 PM
  • 285 views

Brain Activity At The Moment of Death

by Neuroskeptic in Neuroskeptic_Discover

What happens in the brain when we die?



Canadian researchers Loretta Norton and colleagues of the University of Western Ontario examine this grave question in a new paper: Electroencephalographic Recordings During Withdrawal of Life-Sustaining Therapy Until 30 Minutes After Declaration of Death

Norton et al. examined frontal EEG recordings from four critically ill patients at the point where their life support was withdrawn. Here are some details on the four:



Here's the EEG recor... Read more »

Norton L, Gibson RM, Gofton T, Benson C, Dhanani S, Shemie SD, Hornby L, Ward R, & Young GB. (2017) Electroencephalographic Recordings During Withdrawal of Life-Sustaining Therapy Until 30 Minutes After Declaration of Death. The Canadian Journal of Neurological Sciences, 44(2), 139-145. PMID: 28231862  

  • March 3, 2017
  • 02:18 PM
  • 223 views

In memoriam: Eugene Garfield – 1925-2017

by SciELO in SciELO in Perspective

The father of Scientometrics died at 91 years old on February 27, 2017 leaving a production of more than 1.000 papers and communications over 60 years of research. … Read More →... Read more »

  • March 3, 2017
  • 07:02 AM
  • 218 views

Stereotypes, rudeness, sleepy (and punitive) judges,  assumptions and freak airplane accidents

by Rita Handrich in The Jury Room

Time for another combination post of various things you will want to know that will improve your conversation skills and general life knowledge. We are not saying that it will make your hair shiny or inspire your kids to do their homework. Kernels of wisdom, that’s what they are, in truth. Talking to your kids […]... Read more »

Sanchez DT, Chaney KE, Manuel SK, Wilton LS, & Remedios JD. (2017) Stigma by Prejudice Transfer: Racism threatens white women and sexism threatens men of color. Psychological Science. info:/

  • March 3, 2017
  • 05:14 AM
  • 192 views

Rare Disease Day – Findacure Scientific Conference: Drug Repurposing for Rare Diseases

by Joana Guedes in BHD Research Blog

This year’s Findacure Scientific Conference took place in London on Rare Disease Day and was again focused on Drug Repurposing for Rare Diseases. The conference brought together over 100 representatives from patient groups, researchers and members of the healthcare industry to discuss the importance and the latest developments in drug repurposing for rare diseases.... Read more »

  • March 3, 2017
  • 02:56 AM
  • 261 views

Poverty status and autism, ADHD and asthma

by Paul Whiteley in Questioning Answers

The paper by Christian Pulcini and colleagues [1] talking about poverty status potentially influencing "parent-reported lifetime prevalence and comorbidities" when it comes to three target conditions (autism, attention-deficit hyperactivity disorder [ADHD] and asthma) should have been a call to action. Concluding that "poor and near poor children had a higher lifetime prevalence of asthma and ADHD, but not ASD [autism spectrum disorder]" [2], some of the findings have instead attracted crit........ Read more »

Pulcini CD, Zima BT, Kelleher KJ, & Houtrow AJ. (2017) Poverty and Trends in Three Common Chronic Disorders. Pediatrics. PMID: 28193790  

  • March 2, 2017
  • 12:19 PM
  • 258 views

Improving Hearing-Aid Access in Older Adults

by William Yates, M.D. in Brain Posts

There are significant barriers to widespread use of hearing-aids in older adults with age-related hearing loss.Sensitivity to the stigma of wearing a hearing-aid is one barrier.Cost is another significant barrier. In the U.S., bilateral hearing-aid purchase amounts to a cost of $2400 to $5800. This cost is typically not covered by Medicare or other health insurance plans.I ran into a interesting manuscript on looking at an alternative less costlier approach to hearing-aid selection and purchase......... Read more »

  • March 2, 2017
  • 03:11 AM
  • 269 views

Subgroups in autism (without intellectual disability)

by Paul Whiteley in Questioning Answers

"Children with ASD [autism spectrum disorder] without ID [intellectual disability] could be differentiated into Moderate and Severe Social Impairment subgroups when core ASD symptoms were more closely examined."So said the findings reported by Felicity Klopper and colleagues [1] looking at an important part of the autism research scene related to the 'plurality' of the term autism and the seemingly vast range of presentations included under the label. Reliant on data obtained........ Read more »

Felicity Klopper, Renee Testa, Christos Pantelis, & Efstratios Skafidas. (2017) A cluster analysis exploration of autism spectrum disorder subgroups in children without intellectual disability. Research in Autism Spectrum Disorders. info:/10.1016/j.rasd.2017.01.006

  • March 1, 2017
  • 10:30 AM
  • 234 views

What kind of scratching post do cats prefer?

by CAPB in Companion Animal Psychology Blog

It’s important to provide cats with the right kind of scratching post – and reward them for using it.Inappropriate scratching is a fairly common complaint about cats. That’s inappropriate from the owner’s perspective, because from the cat’s point of view they are just doing what comes naturally. Research by Colleen Wilson DVM et al tells us what kind of scratching post to provide in order to keep both cat and owner happy.Cats scratch in order to mark their territory. It leaves a visual........ Read more »

Wilson C, Bain M, DePorter T, Beck A, Grassi V, & Landsberg G. (2016) Owner observations regarding cat scratching behavior: an internet-based survey. Journal of feline medicine and surgery, 18(10), 791-7. PMID: 26179574  

  • March 1, 2017
  • 09:27 AM
  • 229 views

Politics Trump Healthcare Information: News Coverage of the Affordable Care Act

by Jalees Rehman in The Next Regeneration

Gollust and colleagues found that 55% of the news stories either focused on the politics of the ACA such as political disagreements over its implementation (26.5%) or combined information regarding its politics with information on how it would affect healthcare insurance options (28.6%). Only 45% of the news stories focused exclusively on the healthcare insurance options provided by the law. The politics-focused news stories were also more likely to refer to the law as “Obamacare” wh........ Read more »

  • March 1, 2017
  • 08:00 AM
  • 220 views

Transient Imprinting of Genes in the Human Placenta

by Marta Sanchez Delgado in EpiBeat

When the fertilization occurs, the maternal and paternal pronuclei have thousands of opposite methylated regions. Most of this germline methylation are resolved during the postfertilization epigenetic reprogramming by active mechanism for the sperm-derived methylated regions and depending on DNA replication for the oocyte-derived ones. There is a subset of regions that are known to avoid this demethylation: the imprinted differentially methylated regions (DMRs). The imprinted DMRs are in general........ Read more »

Sanchez-Delgado M, Court F, Vidal E, Medrano J, Monteagudo-Sánchez A, Martin-Trujillo A, Tayama C, Iglesias-Platas I, Kondova I, Bontrop R.... (2016) Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting. PLoS genetics, 12(11). PMID: 27835649  

Smallwood SA, & Kelsey G. (2012) De novo DNA methylation: a germ cell perspective. Trends in genetics : TIG, 28(1), 33-42. PMID: 22019337  

Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, & Meissner A. (2014) DNA methylation dynamics of the human preimplantation embryo. Nature, 511(7511), 611-5. PMID: 25079558  

Barbaux S, Gascoin-Lachambre G, Buffat C, Monnier P, Mondon F, Tonanny MB, Pinard A, Auer J, Bessières B, Barlier A.... (2012) A genome-wide approach reveals novel imprinted genes expressed in the human placenta. Epigenetics, 7(9), 1079-90. PMID: 22894909  

Hanna CW, Peñaherrera MS, Saadeh H, Andrews S, McFadden DE, Kelsey G, & Robinson WP. (2016) Pervasive polymorphic imprinted methylation in the human placenta. Genome research, 26(6), 756-67. PMID: 26769960  

  • March 1, 2017
  • 07:02 AM
  • 201 views

So maybe it doesn’t pay to be beautiful  

by Doug Keene in The Jury Room

Or at least, maybe there is no “ugliness penalty” if you are not beautiful. We’ve written a number of times here about the many benefits given to those who are seen as beautiful or attractive. This paper debunks the stereotype and says that salary goes beyond appearance and individual differences matter too. The researchers used […]... Read more »

Kanazawa, S., & Still, MC. (2017) Is there really a beauty premium or an ugliness penalty on earnings?. Journal of Business and Psychology. info:/

  • March 1, 2017
  • 04:30 AM
  • 224 views

Timing is Everything & Fatigue is Inevitable

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Athletes suffered more lower extremity injuries towards the middle to end of the competition and practices, which suggest that fatigue may play a role in lower extremity injury risk.... Read more »

  • March 1, 2017
  • 03:13 AM
  • 260 views

Sex and age might affect comorbidity profiles in autism

by Paul Whiteley in Questioning Answers

The paper by Supekar and colleagues [1] provides some food for thought today specifically with the idea that comorbidity profiles accompanying autism might be influenced by age and gender in mind.To quote: "These results highlight crucial differences between cross-sectional comorbidity patterns and their interactions with sex and age, which may aid in the development of effective sex- and age-specific diagnostic/treatment strategies for ASD [autism spectrum disorder] and comorbid condi........ Read more »

Supekar K, Iyer T, & Menon V. (2017) The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism research : official journal of the International Society for Autism Research. PMID: 28188687  

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