Post List

  • April 21, 2014
  • 05:15 AM
  • 1 view

Lathosterolosis, cholesterol and autism?

by Paul Whiteley in Questioning Answers

Although intrigued by the findings reported by Pier Luigi Calvo and colleagues [1] describing a "unique case" potentially linking liver functions and cognitive functions with a hat-tip to the presentation of autistic behaviours, I'll readily admit that I am way out of my comfort and competence zones when discussing this paper so please be ready with that pinch of salt.How do you like your eggs in the morning? @ Wikipedia As per what the paper and accompanying press release (see he........ Read more »

Calvo, P., Brunati, A., Spada, M., Romagnoli, R., Corso, G., Parenti, G., Rossi, M., Baldi, M., Carbonaro, G., David, E.... (2014) Liver Transplantation in Defects of Cholesterol Biosynthesis: The Case of Lathosterolosis. American Journal of Transplantation. DOI: 10.1111/ajt.12645  

  • April 20, 2014
  • 11:45 PM
  • 6 views

Cross-validation in finance, psychology, and political science

by Artem Kaznatcheev in Evolutionary Games Group

A large chunk of machine learning (although not all of it) is concerned with predictive modeling, usually in the form of designing an algorithm that takes in some data set and returns an algorithm (or sometimes, a description of an algorithm) for making predictions based on future data. In terminology more friendly to the philosophy […]... Read more »

  • April 20, 2014
  • 03:34 PM
  • 24 views

420: How Marijuana Messes With the Brain

by Alexis Delanoir in How to Paint Your Panda

Cannabis use has previously been associated with cognitive impairment, and Smith et al. (2013) showed that heavy marijuana use was associated with poor working memory and brain abnormalities. Now, Gilman et al. (2014) propose that even casual use of marijuana is associated with such negative effects. Is this an issue of correlation/causation, of funding bias, or are the world's weed smokers really in neurological danger? In this post, in celebration of 4/20, I provide context for the recent........ Read more »

Meier, M., Caspi, A., Ambler, A., Harrington, H., Houts, R., Keefe, R., McDonald, K., Ward, A., Poulton, R., & Moffitt, T. (2012) Persistent cannabis users show neuropsychological decline from childhood to midlife. Proceedings of the National Academy of Sciences, 109(40). DOI: 10.1073/pnas.1206820109  

  • April 20, 2014
  • 09:31 AM
  • 24 views

Was Lamarck right after all? A look at epigenetic inheritance

by EE Giorgi in CHIMERAS

Myths © EEGFrom the Wikipedia definition of epigenetics: "In biology, and specifically genetics, epigenetics is the study of heritable changes in gene activity that are not caused by changes in the DNA sequence."Wait a minute... how can we inherit anything that's not encoded in the DNA? All the information we inherit from our parents is coded in the DNA ... Right?That's correct. However, there's something very important that goes hand in hand with the information contained in the genes: how and........ Read more »

  • April 20, 2014
  • 06:03 AM
  • 29 views

The Mystery of “Quantum Resonance Spectroscopy”

by Neuroskeptic in Neuroskeptic_Discover

Can quantum physics help to diagnose schizophrenia and depression? A paper just published in the Journal of Nervous and Mental Disease claims that a technique called ‘quantum resonance spectroscopy’ (QRS) can accurately diagnose various mental health problems. But is it quantum wizardry or magic quackery? According to the authors of the new paper, Zhang et […]The post The Mystery of “Quantum Resonance Spectroscopy” appeared first on Neuroskeptic.... Read more »

Zhang Y, Liu F, Shi J, Yue X, Zhang H, Du X, Sun L, & Yuan J. (2014) Exploratory quantum resonance spectrometer as a discriminator for psychiatric affective disorders. The Journal of nervous and mental disease, 202(4), 287-91. PMID: 24647211  

  • April 19, 2014
  • 02:19 PM
  • 46 views

Introduction to Traditional Peer Review

by Hadas Shema in Information Culture

Peer review was introduced to scholarly publication in 1731 by the Royal Society of Edinburgh, which published a collection of peer-reviewed medical articles. Despite this early start, in many...

-- Read more on ScientificAmerican.com

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Biagioli, M. (2002) From Book Censorship to Academic Peer Review. Emergences: Journal for the Study of Media , 12(1), 11-45. DOI: 10.1080/1045722022000003435  

Benos DJ, Bashari E, Chaves JM, Gaggar A, Kapoor N, LaFrance M, Mans R, Mayhew D, McGowan S, Polter A.... (2007) The ups and downs of peer review. Advances in physiology education, 31(2), 145-52. PMID: 17562902  

Bornman, L. (2008) Scientific Peer Review: An Analysis of the Peer Review Process from the Perspective of Sociology of Science Theories. Human Architecture: Journal of the Sociology of Self-Knowledge, 6(2). info:/

Brown, R. (2006) Double Anonymity and the Peer Review Process. The Scientific World JOURNAL, 1274-1277. DOI: 10.1100/tsw.2006.228  

Callaham ML, Baxt WG, Waeckerle JF, & Wears RL. (1998) Reliability of editors' subjective quality ratings of peer reviews of manuscripts. JAMA : the journal of the American Medical Association, 280(3), 229-31. PMID: 9676664  

Spier R. (2002) The history of the peer-review process. Trends in biotechnology, 20(8), 357-8. PMID: 12127284  

  • April 19, 2014
  • 12:51 PM
  • 51 views

First female “penis” discovered in cave-dwelling insects

by beredim in Strange Animals

Image showing the female penis of N. auroraCredit: Current Biology, Yoshizawa et al.Kingdom: AnimaliaPhylum: ArthropodaClass: InsectaOrder: PsocopteraFamily: PrionoglarididaeGenus: NeotroglaSpecies: N. aurora, N. curvet and 2 otherThis Thursday, researchers announced that they have discovered several insect species that display the "world's first" known instance of gender-reversed genitalia. In simple words, they have found 4 insect species with female... "penises." and male "vaginae"!........ Read more »

  • April 19, 2014
  • 07:34 AM
  • 48 views

Typing Method for Cryptosporidium Meleagridis

by Christen Rune Stensvold in Christen Rune Stensvold

You can read about the development and use of a highly applicable typing method for C. meleagridis isolates in a newly published paper in Journal of Clinical Microbiology.... Read more »

  • April 19, 2014
  • 07:34 AM
  • 50 views

Typing Method for Cryptosporidium Meleagridis

by Christen Rune Stensvold in Blastocystis Parasite Blog

You can read about the development and use of a highly applicable typing method for C. meleagridis isolates in a newly published paper in Journal of Clinical Microbiology.... Read more »

  • April 19, 2014
  • 05:34 AM
  • 40 views

Dump fossil fuels for the health of our hearts

by Andy Extance in Simple Climate

Cleaning up air pollution will provide immediate health gains as well as longer-term climate benefits, highlights New York University's George Thurston... Read more »

Thurston, G. (2013) Mitigation policy: Health co-benefits. Nature Climate Change, 3(10), 863-864. DOI: 10.1038/nclimate2013  

Rice, M., Thurston, G., Balmes, J., & Pinkerton, K. (2014) Climate Change. A Global Threat to Cardiopulmonary Health. American Journal of Respiratory and Critical Care Medicine, 189(5), 512-519. DOI: 10.1164/rccm.201310-1924PP  

  • April 19, 2014
  • 05:32 AM
  • 44 views

The nose knows: How to pick your friends

by Teodora Stoica in CuriousCortex

The importance of human odor in a social context. ... Read more »

  • April 19, 2014
  • 12:46 AM
  • 38 views

Energy Expenditure (Calories Burned) in Anorexia Nervosa Patients

by Tetyana in Science of Eating Disorders


How many calories do patients with anorexia nervosa need to eat to gain a kilo (2.2 lbs)? It seems like a simple question and one that we should have figured out a long time ago, given the importance (err, necessity) of refeeding and weight restoration in recovery from anorexia nervosa.
Unfortunately, research in this area has often led to contradictory results (see Salisbury et al., 1995 and de Zwaan et al., 2002 for reviews). Fortunately, a paper by Stephan Zipfel and colleagues (2013,........ Read more »

Zipfel S, Mack I, Baur LA, Hebebrand J, Touyz S, Herzog W, Abraham S, Davies PS, & Russell J. (2013) Impact of exercise on energy metabolism in anorexia nervosa. Journal of Eating Disorders, 1(1), 37. PMID: 24499685  

  • April 18, 2014
  • 01:56 PM
  • 53 views

Moving Beyond “Just-So Stories”: Young Children Can Be Taught Basic Natural Selection

by amikulak in Daily Observations

Spend more than a few hours with a child under the age of 10 and “why?” is a question you’re likely to hear a. Children are naturally curious explorers, and […]... Read more »

  • April 18, 2014
  • 01:07 PM
  • 19 views

Overcomming Social Phobia with CBT and Pharmacotherapy

by Vivek Misra in Uber Notions

photo credit: ParadigmMalibu.comSocial phobia, a type of anxiety disorder, is characterized by persistent fear of one or more social or performance situations in which the person is exposed to unfamiliar people or to possible scrutiny by others (1). The individual fears that he or she will act in a way (or show anxiety symptoms) that will be embarrassing and humiliating.  Exposure to the feared situation almost invariably provokes anxiety, which may take the form of a situationally bou........ Read more »

Domschke K, Stevens S, Beck B, Baffa A, Hohoff C, Deckert J, & Gerlach AL. (2009) Blushing propensity in social anxiety disorder: influence of serotonin transporter gene variation. Journal of neural transmission (Vienna, Austria : 1996), 116(6), 663-6. PMID: 18629430  

Nahshoni E, Gur S, Marom S, Levin JB, Weizman A, & Hermesh H. (2004) QT dispersion in patients with social phobia. Journal of affective disorders, 78(1), 21-6. PMID: 14672793  

  • April 18, 2014
  • 11:04 AM
  • 49 views

Danish Project to Make Polymer Solar Cells More Profitable

by dailyfusion in The Daily Fusion

Project Megawatt intends to make polymer solar cells profitable enough to allow power generation from polymer solar cells to compete on market terms with traditional coal-fired power plants.... Read more »

  • April 18, 2014
  • 09:09 AM
  • 40 views

Corporate Culture Directly Affects Financial Performance

by Jeremiah Stanghini in Jeremiah Stanghini

The question as to whether corporate culture has an effect on financial performance has been asked before and it will likely be asked again. In a study published in the Cornell Hospitality Quarterly, research demonstrated a link between corporate culture and … Continue reading →... Read more »

  • April 18, 2014
  • 07:02 AM
  • 58 views

Hey, trial lawyers! The FDA is watching you!

by Doug Keene in The Jury Room

And they want you to stop abusing their Adverse Event Reporting System (FAERS). We’ve worked a number of cases recently where FDA warnings were used as evidence at trial and were very interested to see this article in the American Journal of Gastroenterology. And the answer to the skeptic’s question is “no”. No, we don’t […]

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Predic........ Read more »

Racine A, Cuerq A, Bijon A, Ricordeau P, Weill A, Allemand H, Chosidow O, Boutron-Ruault MC, & Carbonnel F. (2014) Isotretinoin and risk of inflammatory bowel disease: a French nationwide study. The American Journal of Gastroenterology, 109(4), 563-9. PMID: 24535094  

  • April 17, 2014
  • 11:02 PM
  • 140 views

Dear CNRS: That mouse study did not "confirm" the neurobiological origin of ADHD in humans

by in Neuroscientifically Challenged

Late last week the French National Centre for Scientific Research (CNRS - the acronym is based on the French translation) put out a press release describing a study conducted through a collaboration between several of its researchers and scientists from The University of Strasbourg. CNRS is a large (30,000+ employees), government-run research institution in France. It is the largest research organization in Europe, and is responsible for about 1/2 of the French scientific papers published annual........ Read more »

  • April 17, 2014
  • 05:57 PM
  • 55 views

Li-Sulfur Batteries Last Longer With Metal-Organic Frameworks

by dailyfusion in The Daily Fusion

Researchers at the PNNL added a kind of nanomaterial called a metal-organic framework, to the battery’s cathode to capture problematic polysulfides that usually cause lithium-sulfur batteries to fail after a few charges.... Read more »

  • April 17, 2014
  • 05:45 PM
  • 30 views

X-Rays Help Understand High-Temperature Superconductivity

by dailyfusion in The Daily Fusion

A new study pins down a major factor behind the appearance of laser-induced high-temperature superconductivity in a promising copper-oxide material.... Read more »

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