Post List

  • October 24, 2014
  • 06:49 AM
  • 0 views

Blocking Key Gene To Stop Malaria Transmission

by Pieter Carrière in United Academics

Earlier this week Pieter wrote about a key gene in the transmission of Malaria. Now he explains more about blocking this gene to prevent spreading.... Read more »

Kafsack BF, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA.... (2014) A transcriptional switch underlies commitment to sexual development in malaria parasites. Nature, 507(7491), 248-52. PMID: 24572369  

Kåhrström CT. (2014) Parasite development: master regulator of sex. Nature reviews. Microbiology, 12(4), 233. PMID: 24608336  

Rovira-Graells N, Gupta AP, Planet E, Crowley VM, Mok S, Ribas de Pouplana L, Preiser PR, Bozdech Z, & Cortés A. (2012) Transcriptional variation in the malaria parasite Plasmodium falciparum. Genome research, 22(5), 925-38. PMID: 22415456  

Gardner, M., Hall, N., Fung, E., White, O., Berriman, M., Hyman, R., Carlton, J., Pain, A., Nelson, K., Bowman, S.... (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature, 419(6906), 498-511. DOI: 10.1038/nature01097  

  • October 24, 2014
  • 04:27 AM
  • 7 views

Collective Structures in Software Projects

by Jörg Friedrich in Software Engineering Economics

To understand the social dynamics of complex software development processes, it is necessary to analyze in which structures the persons involved and how this involvement affected their work. Damian Tamburri has in recent years identified the relevant social structures in a number of publications, analyzed and graded on their effect. He first distinguishes four basic […]... Read more »

Tamburri, D., Lago, P., & Vliet, H. (2013) Organizational social structures for software engineering. ACM Computing Surveys, 46(1), 1-35. DOI: 10.1145/2522968.2522971  

  • October 24, 2014
  • 02:51 AM
  • 13 views

Autism, siblings and DSM-5 Social Communication Disorder

by Paul Whiteley in Questioning Answers

A quick post to bring to your attention the paper by Meghan Miller and colleagues [1] who concluded that: "Pragmatic language problems are present in some siblings of children with ASD [autism spectrum disorder] as early as 36 months of age". Further: "As the new DSM-5 diagnosis of Social (Pragmatic) Communication Disorder (SCD) is thought to occur more frequently in family members of individuals with ASD, it is possible that some of these siblings will meet criteria for SCD as th........ Read more »

  • October 24, 2014
  • 12:05 AM
  • 3 views

Who is at Risk for Medial Tibial Stress Syndrome?

by Hallie Labrador MD, MS in Sports Medicine Research (SMR): In the Lab & In the Field

Risk of medial tibial stress syndrome (MTSS) is associated with increased body mass index, navicular drop, ankle plantarflexion range of motion (ROM) and hip external rotation ROM.... Read more »

  • October 23, 2014
  • 05:58 PM
  • 23 views

The Genes Responsible for Immune System Reset after Infection

by Gabriel in Lunatic Laboratories

We’ve all been sick before, the aches and pains that come with it– most of the time including a fever — are all responses to our immune system kicking into high gear. But what if your body didn’t reverse course and go back to a, let’s call it” relaxed state.” Once the battle is won, the body’s efforts would be wasted on energy costing defense. A bad thing when the body really should be focusing on repairing the damage done by the foreign invaders.... Read more »

Brian Head,, & Alejandro Aballay. (2014) Recovery from an Acute Infection in C. elegans Requires the GATA Transcription Factor ELT-2. PLoS Genetics. info:/10.1371/journal.pgen.1004609

  • October 23, 2014
  • 10:20 AM
  • 26 views

Smartphone App Boosts Alcoholism Treatment Outcome

by William Yates, M.D. in Brain Posts

Smartphone apps and other mobile technology are emerging as promising tools in medical treatment.A recent randomized study published in JAMA Psychiatry found evidence that a smartphone app improves alcoholism treatment outcomes.David Gustafson and colleagues conducted a study funded by the National Institute of Alcohol Abuse and Alcoholism.A series of 349 adults with DSM-IV alcohol dependence were enrolled as they entered a alcoholism residential treatment program.Approximately half of the subje........ Read more »

Gustafson DH, McTavish FM, Chih MY, Atwood AK, Johnson RA, Boyle MG, Levy MS, Driscoll H, Chisholm SM, Dillenburg L.... (2014) A smartphone application to support recovery from alcoholism: a randomized clinical trial. JAMA psychiatry, 71(5), 566-72. PMID: 24671165  

  • October 23, 2014
  • 09:05 AM
  • 32 views

The Monster Mash – Diseases That May Have Spawned Monster Legends

by Bill Sullivan in The 'Scope

Creepy diseases that produce symptoms that mimic characteristics associated with legendary monsters!... Read more »

Schulenburg-Brand D, Katugampola R, Anstey AV, & Badminton MN. (2014) The cutaneous porphyrias. Dermatologic clinics, 32(3), 369. PMID: 24891059  

Deshmukh S, & Prashanth S. (2012) Ectodermal dysplasia: a genetic review. International journal of clinical pediatric dentistry, 5(3), 197-202. PMID: 25206167  

Ramirez-Bermudez J, Aguilar-Venegas LC, Crail-Melendez D, Espinola-Nadurille M, Nente F, & Mendez MF. (2010) Cotard syndrome in neurological and psychiatric patients. The Journal of neuropsychiatry and clinical neurosciences, 22(4), 409-16. PMID: 21037126  

  • October 23, 2014
  • 07:38 AM
  • 36 views

Four Solar-Powered Animals

by beredim in Strange Animals

Photosynthesis, a process used by plants and some bacteria to convert light from the sun into chemical energy which can be later released to fuel their activities. Animals on the other hand, have to consume other organisms in order to cover their energy needs. But every rule has an exception.In recent years, researchers have discovered a small number of animals that much like plants have found a way to directly harness and feed off the Sun’s energy.1# Oriental Hornet (Vespa orientalis)Typicall........ Read more »

Rumpho ME, Worful JM, Lee J, Kannan K, Tyler MS, Bhattacharya D, Moustafa A, & Manhart JR. (2008) Horizontal gene transfer of the algal nuclear gene psbO to the photosynthetic sea slug Elysia chlorotica. Proceedings of the National Academy of Sciences of the United States of America, 105(46), 17867-71. PMID: 19004808  

Plotkin M, Hod I, Zaban A, Boden SA, Bagnall DM, Galushko D, & Bergman DJ. (2010) Solar energy harvesting in the epicuticle of the oriental hornet (Vespa orientalis). Die Naturwissenschaften, 97(12), 1067-76. PMID: 21052618  

Valmalette, J., Dombrovsky, A., Brat, P., Mertz, C., Capovilla, M., & Robichon, A. (2012) Light- induced electron transfer and ATP synthesis in a carotene synthesizing insect. Scientific Reports. DOI: 10.1038/srep00579  

Kerney, R., Kim, E., Hangarter, R., Heiss, A., Bishop, C., & Hall, B. (2011) Intracellular invasion of green algae in a salamander host. Proceedings of the National Academy of Sciences, 108(16), 6497-6502. DOI: 10.1073/pnas.1018259108  

  • October 23, 2014
  • 07:02 AM
  • 32 views

How reminders of money affect people's expression and perception of emotion

by BPS Research Digest in BPS Research Digest

Bank robbers and gamblers will tell you what people are prepared to do for the sake of money. But money also has more subtle influences. Back in 2006, researchers showed that mere reminders of money made people more selfish (although note a later attempt failed to replicate this result).In the latest research in this field, a team led by Yuwei Jiang have shown that exposing people to pictures of money, or to money-related words, reduces their emotional expressivity and makes them more sensitive ........ Read more »

Jiang, Y., Chen, Z., & Wyer, R. (2014) Impact of money on emotional expression. Journal of Experimental Social Psychology, 228-233. DOI: 10.1016/j.jesp.2014.07.013  

  • October 23, 2014
  • 04:46 AM
  • 34 views

Postpartum depression and the broader autism phenotype?

by Paul Whiteley in Questioning Answers

"The findings suggest that pregnant women with BAP [broader autism phenotype] have an elevated risk for PPD [postpartum depression]".That was the conclusion reached by Ryosuke Asano and colleagues [1] based on their analysis of data derived from the Hamamatsu Birth Cohort (HBC) Study [2]. The idea being that the more subtle presentation of issues linked to a diagnosis of autism spectrum disorder (the BAP) might predispose to a great likelihood of other behavioural or psychiat........ Read more »

Asano, R., Tsuchiya, K., Takei, N., Harada, T., Kugizaki, Y., Nakahara, R., Nakayasu, C., Okumura, A., Suzuki, Y., Takagai, S.... (2014) Broader autism phenotype as a risk factor for postpartum depression: Hamamatsu Birth Cohort (HBC) Study. Research in Autism Spectrum Disorders, 8(12), 1672-1678. DOI: 10.1016/j.rasd.2014.08.010  

  • October 22, 2014
  • 11:05 PM
  • 37 views

Microscopic observation in live tissue, awesome! But don’t ignore the methods

by Austin Bouck in Animal Science Review

The NIH sent me an email this week (via the various government listservs I’m enrolled in) that was proudly declaring that the mysteries of the cell were being solved right now, so I took the clickbait. In it was a cool study where we were able to actively watch mitochondria oscillate inside a living animal...... Read more »

Natalie Porat-Shliom, Yun Chen, Muhibullah Tora, Akiko Shitara, Andrius Masedunskas, & Roberto Weigertemail. (2014) In Vivo Tissue-wide Synchronization of Mitochondrial Metabolic Oscillations. Cell Reports. info:/http://dx.doi.org/10.1016/j.celrep.2014.09.022

Weigert R, Porat-Shliom N, & Amornphimoltham P. (2013) Imaging cell biology in live animals: ready for prime time. The Journal of cell biology, 201(7), 969-79. PMID: 23798727  

  • October 22, 2014
  • 03:55 PM
  • 47 views

Converting Skin Cells to Neurons: A Fight Against Huntington’s

by Gabriel in Lunatic Laboratories

Neurological diseases are some of the hardest to fight against (in my opinion). The big reason is the brain, we still know so little about it and treatment for anything effecting it can be difficult to say the least. Take Huntington’s disease, an ultimately fatal neurodegenerative disorder. There is no cure and no real treatment, but that might change relatively soon thanks to a new discovery.... Read more »

Victor, M., Richner, M., Hermanstyne, T., Ransdell, J., Sobieski, C., Deng, P., Klyachko, V., Nerbonne, J., & Yoo, A. (2014) Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts. Neuron, 84(2), 311-323. DOI: 10.1016/j.neuron.2014.10.016  

  • October 22, 2014
  • 11:21 AM
  • 52 views

Are All Labrador Retrievers the Same?

by CAPB in Companion Animal Psychology Blog

Or do show dogs and field dogs vary in temperament?Photo: c.byatt-norman / ShutterstockIt’s often said there are personality differences between Labrador Retrievers bred to show (conformation dogs) and those bred to work (field dogs). And chocolate labs have a reputation for being different than black and yellow labs. Is it true? New research by Sarah Lofgren et al (Royal (Dick) Veterinary School, University of Edinburgh) investigates.Although many Labrador Retrievers are family pets, some&nbs........ Read more »

Lofgren, S., Wiener, P., Blott, S., Sanchez-Molano, E., Woolliams, J., Clements, D., & Haskell, M. (2014) Management and personality in Labrador Retriever dogs. Applied Animal Behaviour Science, 44-53. DOI: 10.1016/j.applanim.2014.04.006  

  • October 22, 2014
  • 09:46 AM
  • 48 views

Video Tip of the Week: SeqMonk

by Mary in OpenHelix

Always on the lookout for effective visualization tools, I recently came across a series of videos about the SeqMonk software. It’s not software that I had used before, so I wanted to look at the videos, and then try it out. It downloaded quickly, offered me an extensive list of genomes to load up, and […]... Read more »

  • October 22, 2014
  • 08:05 AM
  • 48 views

Death By Haunted House

by Mark Lasbury in As Many Exceptions As Rules

People enjoy a good scare at Halloween, it’s an epinephrine rush without the bother of real danger. But could you actually be scared to death? Science says yes, it should really be called the fight, flight, faint, or fatality response. In susceptible people, a severe fright can literally change the shape of the heart and destroy the efficient pumping of blood. Unfortunately, something similar can happen in infants, and it can be lethal as well.... Read more »

  • October 22, 2014
  • 07:29 AM
  • 39 views

Crucial gene for Malaria Transmission

by Pieter Carrière in United Academics

A new step in battling Malaria: making transmission its weakest link. Scientists could prevent the development of gametocytes.... Read more »

Kafsack BF, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA.... (2014) A transcriptional switch underlies commitment to sexual development in malaria parasites. Nature, 507(7491), 248-52. PMID: 24572369  

Kåhrström CT. (2014) Parasite development: master regulator of sex. Nature reviews. Microbiology, 12(4), 233. PMID: 24608336  

Rovira-Graells N, Gupta AP, Planet E, Crowley VM, Mok S, Ribas de Pouplana L, Preiser PR, Bozdech Z, & Cortés A. (2012) Transcriptional variation in the malaria parasite Plasmodium falciparum. Genome research, 22(5), 925-38. PMID: 22415456  

Gardner, M., Hall, N., Fung, E., White, O., Berriman, M., Hyman, R., Carlton, J., Pain, A., Nelson, K., Bowman, S.... (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature, 419(6906), 498-511. DOI: 10.1038/nature01097  

  • October 22, 2014
  • 05:10 AM
  • 38 views

Five-year-olds can see through your bravado

by BPS Research Digest in BPS Research Digest

Imagine you wanted to lie to a five-year-old. "The toy shop is closed Billy," you say, "it always closes at 2pm on a Monday." You reason that if you make this announcement with confidence, then Billy is sure to believe you.It's not a bad strategy. In a new study involving nearly a hundred kids aged four to five, they were more likely to believe statements made by a woman who spoke and gestured with confidence, than those made by a woman who was hesitant and uncertain. In this case, the women's c........ Read more »

  • October 22, 2014
  • 04:38 AM
  • 33 views

Can a brain scan tell us anything about the art of creative writing?

by BPS Research Digest in BPS Research Digest

When an accomplished creative writer gets on with their craft, their brain operates in a somewhat different way to a novice's. A new imaging study suggests that the expert approach may be more streamlined, emotionally literate, and initially unfiltered.Katharina Erhard with her colleagues from the German universities of Greifswald and Hildesheim asked participants to read a fragment of a story, to brainstorm what could continue the narrative, and then, for two minutes, to write a continuation of........ Read more »

  • October 22, 2014
  • 04:26 AM
  • 49 views

Autism, parental concerns and socioeconomic status

by Paul Whiteley in Questioning Answers

I'd like to think that there are some rather important messages to be taken from the paper by Xiang Sun and colleagues [1] on level of parental concern, socioeconomic status (SES) and risk of autism. Not only did the authors conclude that: "a higher SES was not associated with the risk of having ASC [autism spectrum conditions]" they also found that: "No child met ASC criteria where parents expressed no concerns".Do you prefer "fashion victim" or "ensembly challenged"?SES - including variab........ Read more »

  • October 22, 2014
  • 12:05 AM
  • 46 views

Knee Cartilage Changes Following ACL Rupture

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Following an anterior cruciate ligament (ACL) rupture overall cartilage thickness in the tibiofemoral joint increased at an average of 0.4% per year. Patients under 25 years of age showed greater cartilage thickening than older patients.... Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.