Geophysicists are scouring the globe for evidence of mantle plumes — the presumed source of some mega-eruptions.
Further reading... Read more »
Scientists have developed new DNA vaccine for vascular endothelial growth factor (VEGF) that could prolong survival in cancer and can improve cancer treatment strategies.
Vascular endothelial growth factor (VEGF):
VEGF is a protein produced by cells to activate formation of blood vessels. This process helps in restoring the oxygen supply to the tissues in case of improper blood circulation. Although, it is a good proce........ Read more »
Mariko Kyutoku et al. (2013) Development of novel DNA vaccine for VEGF in murine cancer model. Scientific Reports. DOI: 10.1038/srep03380
Stanford researchers have uncovered a vital clue about the mechanism behind a type of earthquake that originates deep within the Earth and accounts for a quarter of all temblors worldwide, some of which are strong enough to pose a safety hazard.... Read more »
Germán A. Prieto, Manuel Florez, Sarah A. Barrett, Gregory C. Beroza, Patricia Pedraza, Jose Faustino Blanco, & Esteban Poveda. (2013) Seismic evidence for thermal runaway during intermediate-depth earthquake rupture. Geophysical Research Letters. DOI: 10.1002/2013GL058109
Cell under the microscopeCredit: iStockMuscle cell therapy to treat some degenerative diseases, including Muscular Dystrophy, is now a step closer, according to a new study by researchers from the Australian Regenerative Medicine Institute (ARMI) at the Monash University.PhD Student Bianca Borchin and Associate Professor Tiziano Barberi have developed a method to generate skeletal muscle cells, paving the way for future applications in regenerative medicine.Scientists, for the first time, have ........ Read more »
Bianca Borchin, Joseph Chen, Tiziano Barberi. (2013) Derivation and FACS-Mediated Purification of PAX3 /PAX7 Skeletal Muscle Precursors from Human Pluripotent Stem Cells. Stem Cell Reports. DOI: 10.1016/j.stemcr.2013.10.007
Gut inflammation and autism.Laughing or smirking? Wikipedia Words which still have the ability to furrow brows and precipitate eye rolling. Whatever your views on this topic, whether based on science or politics or both, there is no getting away from the evidence suggestive that in SOME cases of autism, issues with that deepest, darkest realm - the gut - do seem to be present.Whether based on the presence of functional bowel issues (see here and here) or something rather more fundamental (s........ Read more »
de Theije CG, Koelink PJ, Korte-Bouws GA, Silva SL, Mechiel Korte S, Olivier B, Garssen J, & Kraneveld AD. (2013) Intestinal inflammation in a murine model of autism spectrum disorders. Brain Behav Immun. DOI: 10.1016/j.bbi.2013.12.004
High-density lipoprotein (HDL), known colloquially as “good cholesterol”, protects against dangerous deposits in the arteries. An important function of HDL is its anti-inflammatory properties. An international research team at the Institute of Innate Immunity at the University Hospital of Bonn and the LIMES Institute at the University of Bonn has identified a central switch by which HDL controls the inflammatory response. The results are presented in the current issue of “Natur........ Read more »
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA.... (2013) High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nature immunology. PMID: 24317040
Cruz PM, Mo H, McConathy WJ, Sabnis N, & Lacko AG. (2013) The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics. Frontiers in pharmacology, 119. PMID: 24093019
The crying was associated with a sorrowful facial expression, sobbing body movements, and a voice inflected with sadness. These physical manifestations ended with the termi- nation of stimulation and the patient described feeling sad, but could not express the trigger for the sadness or crying. Results were consistent and reproducible. I have previously wondered why […]... Read more »
Burghardt T, Basha MM, Fuerst D, & Mittal S. (2013) Crying with sorrow evoked by electrocortical stimulation. Epileptic disorders : international epilepsy journal with videotape, 15(1), 72-5. PMID: 23531727
This image was provided by the CDC and the Partnership, Inc. Available at Wikimedia Commons.Studies of the spread of infectious diseases have shown that behavior plays a strong role in which individuals are more likely to be infected and which ones aren't. For example, sexually transmitted diseases (STDs) are more commonly diagnosed in people that have more sexual partners. But despite our understanding of how diseases are spread among people, we know very little about the spread of diseases amo........ Read more »
Dizney L, & Dearing MD. (2013) The role of behavioural heterogeneity on infection patterns: implications for pathogen transmission. Animal behaviour, 86(5). PMID: 24319292
As the US seeks to expand its wind energy sector, a new study sheds greater light on the impact of wind turbines on wildlife. ... Read more »
Scott R. Loss, Tom Will, & Peter P. Mara. (2013) Estimates of bird collision mortality at wind facilities in the contiguous United States. Biological Conservation, 201-209. DOI: 10.1016/j.biocon.2013.10.007
Over the years we’ve seen some real shifts in the needs of the trainees in our UCSC Genome Browser workshops. At first, people just needed access to the reference genome and the data that was available (and boy, has that changed over the years–time travel back with this post!). But as researchers around the world […]... Read more »
Raney B. J., Dreszer T. R., Barber G. P., Clawson H., Fujita P. A., Wang T., Nguyen N., Paten B., Zweig A. S., & Karolchik D. (2013) Track data hubs enable visualization of user-defined genome-wide annotations on the UCSC Genome Browser. Bioinformatics. DOI: 10.1093/bioinformatics/btt637
In a new project dubbed AGORA, researchers are working to remove the discrepancies among different computer models of galaxy formation by comparing different codes against each other.
The project AGORA is the short form for Assembling Galaxies of Resolved Anatomy. “We investigate galaxy formation with high-resolution numerical simulations and compare the results across different platforms, and with observation,” Project AG........ Read more »
Ji-hoon Kim, Tom Abel, Oscar Agertz, Greg L. Bryan, Daniel Ceverino, Charlotte Christensen, Charlie Conroy, Avishai Dekel, Nickolay Y. Gnedin, Nathan J. Goldbaum.... (2013) The AGORA High-Resolution Galaxy Simulations Comparison Project. arXiv. arXiv: 1308.2669v4
Health experts say we aren't eating enough fruit. Perhaps psychology can help. Try this. Picture yourself eating a portion of fruit tomorrow - an apple, say, or a couple of plums. Take your time. Focus on the colours, the consistency, the flavour. Visualise where you are at the time, and what you are doing.Do you think this simple imagery task will have increased the likelihood you will eat fruit tomorrow? A new study led by Catherine Adams attempted to find out. Over two hundred volunteers were........ Read more »
Adams C, Rennie L, Uskul AK, & Appleton KM. (2013) Visualising future behaviour: Effects for snacking on biscuit bars, but no effects for snacking on fruit. Journal of health psychology. PMID: 24217063
Dogs are social creatures, but while some dogs clearly love to visit dog parks, others seem less happy about it. New research by Ottenheimer Carrier et al (Memorial University of Newfoundland) investigates whether the dog park is stressful, and what dogs do there.Photo: Gerald Marella / ShutterstockDog parks are open spaces, usually fenced, where dogs can be off-leash. They are particularly useful in municipalities where leash laws mean there are few spaces for dogs to run free. The researchers ........ Read more »
Ottenheimer Carrier, L., Cyr, A., Anderson, R.E., & Walsh, C.J. (2013) Exploring the dog park: Relationships between social behaviours, personality and cortisol in companion dogs. Applied Animal Behaviour Science , 96-106. DOI: 10.1016/j.applanim.2013.04.002
Phospholipids are just one type of lipid in all cells. The fatty acids are the precursor to all kinds of lipids, but in some cases they have been modified to such a degree that they are not identifiable. The fatty acids are showing interesting functions, such as a new study showing that the levels of odd chain fatty acids can be used to monitor rumen health in cattle. The omega fatty acids are also becoming important in the treatment and prevention of depression. A new study shows that in Ameri........ Read more »
Beydoun MA, Fanelli Kuczmarski MT, Beydoun HA, Hibbeln JR, Evans MK, & Zonderman AB. (2013) ω-3 Fatty Acid Intakes Are Inversely Related to Elevated Depressive Symptoms among United States Women. The Journal of nutrition, 143(11), 1743-52. PMID: 24005610
Li Z, Thiel K, Thul PJ, Beller M, Kühnlein RP, & Welte MA. (2012) Lipid droplets control the maternal histone supply of Drosophila embryos. Current biology : CB, 22(22), 2104-13. PMID: 23084995
Vlaeminck B, Dufour C, van Vuuren AM, Cabrita AR, Dewhurst RJ, Demeyer D, & Fievez V. (2005) Use of odd and branched-chain fatty acids in rumen contents and milk as a potential microbial marker. Journal of dairy science, 88(3), 1031-42. PMID: 15738238
The hormonal mayhem, reduced fertility and hot flushes experienced by a woman in the run up to menopause may owe much to warfare between her own genes, according to a team of scientists working in the United Kingdom and Japan.... Read more »
Francisco Úbeda, Hisashi Ohtsuki, & Andy Gardner. (2013) Ecology drives intragenomic conflict over menopause. Ecology Letters. DOI: 10.1111/ele.12208
by Rita Handrich in The Jury Room
It’s been a while since we’ve done an update on neurolaw in the courtroom. The idea that pretty and colorful pictures of the brain (aka fMRIs) can give us a window into motivations, intent, and the creepiness of others captures our imagination. New research though, cautions us that perhaps (like the vast over-estimations of the […]
Confused about brain scans? Welcome to the club!
Defending the Psychopath: “His brain made him do it”
On brains, brain damage, pedophili........ Read more »
Hook CJ, & Farah MJ. (2013) Look again: effects of brain images and mind-brain dualism on lay evaluations of research. Journal of Cognitive Neuroscience, 25(9), 1397-405. PMID: 23879877
Schweitzer NJ, Baker DA, & Risko EF. (2013) Fooled by the brain: re-examining the influence of neuroimages. Cognition, 129(3), 501-11. PMID: 24041836
Investigators have found that they can use PET plastic bottles as raw-material to manufacture a biomaterial, which will disrupt fungi cells’ outer membrane. Therefore, it prevents the fungi’s cell division and ultimately, it causes the fungi’s death.... Read more »
Fukushima K, Liu S, Wu H, Engler AC, Coady DJ, Maune H, Pitera J, Nelson A, Wiradharma N, Venkataraman S.... (2013) Supramolecular high-aspect ratio assemblies with strong antifungal activity. Nature communications, 2861. PMID: 24316819
Air pollution.I'm pretty sure most people are aware of all the talk about air pollution these days and how the human body is not particularly fond of air pollution in terms of potential adverse health outcomes (assuming that is, you leave things like selenium out of the equation). If you happen to live in China, I'm sure your mind was put at ease when reading about 'The Five Surprising Gains from the Smog'... or maybe not.Most people generally find it easier to accept that air pollution might sh........ Read more »
Volk HE, Kerin T, Lurmann F, Hertz-Picciotto I, McConnell R, & Campbell DB. (2013) Autism Spectrum Disorder: Interaction of Air Pollution with the MET Receptor Tyrosine Kinase Gene. Epidemiology (Cambridge, Mass.). PMID: 24240654
Standardised methods and broadly accepeted reference data are the bread and butter of molecular epidemiological studies of infectious organisms. This post highlights some of the issues related to molecular epidemiology terminology and draws parallels between research in Blastocystis and Cryptosporidium.... Read more »
Alfellani MA, Taner-Mulla D, Jacob AS, Imeede CA, Yoshikawa H, Stensvold CR, & Clark CG. (2013) Genetic diversity of blastocystis in livestock and zoo animals. Protist, 164(4), 497-509. PMID: 23770574
Šlapeta J. (2013) Cryptosporidiosis and Cryptosporidium species in animals and humans: a thirty colour rainbow?. International journal for parasitology, 43(12-13), 957-70. PMID: 23973380
Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF.... (2013) Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet, 382(9888), 209-22. PMID: 23680352
Stensvold CR, Suresh GK, Tan KS, Thompson RC, Traub RJ, Viscogliosi E, Yoshikawa H, & Clark CG. (2007) Terminology for Blastocystis subtypes--a consensus. Trends in parasitology, 23(3), 93-6. PMID: 17241816
Xiao L, Ryan UM, Fayer R, Bowman DD, & Zhang L. (2012) Cryptosporidium tyzzeri and Cryptosporidium pestis: which name is valid?. Experimental parasitology, 130(3), 308-9. PMID: 22230707
Striepen B. (2013) Parasitic infections: Time to tackle cryptosporidiosis. Nature, 503(7475), 189-91. PMID: 24236315
Hip exercises consistently provide greater improvements for patellofemoral pain syndrome (PFPS) than knee exercises alone. However, any exercise provides alleviation from PFPS. ... Read more »
Peters JS, & Tyson NL. (2013) Proximal exercises are effective in treating patellofemoral pain syndrome: a systematic review. International Journal of Sports Physical Therapy, 8(5), 689-700. PMID: 24175148
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